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Risk factors for failure of hydrostatic reduction in children with intussusception in Hasan Sadikin General Hospital
D D Kusmayadi1, L K Agnestivita2, V Indriasari1
1Padjadjaran University, Hasan Sadikin General Hospital, Faculty of Medicine, Department of Surgery, Pediatric Surgery Division, Bandung, Indonesia.
Insights
Dehydration significantly increases the risk of hydrostatic reduction failure in pediatric intussusception cases. This finding is crucial for managing this medical emergency in children.
Area of Science:
- Pediatric Gastroenterology
- Surgical Outcomes
- Medical Emergencies
Background:
- Intussusception is a critical pediatric condition requiring prompt management.
- Surgical reduction is standard, but hydrostatic reduction offers a less invasive approach.
- Understanding factors influencing hydrostatic reduction success is vital for optimizing patient care.
Purpose of the Study:
- To identify risk factors associated with the failure of hydrostatic reduction in pediatric intussusception.
- To analyze patient characteristics and their correlation with hydrostatic reduction outcomes.
- To provide data for improving non-invasive treatment strategies for intussusception.
Main Methods:
- Retrospective analysis of medical records for children with intussusception treated via hydrostatic reduction (January 2010-September 2019).
- Inclusion of variables: age, sex, symptom onset, and outcome.
- Logistic regression analysis to determine significant predictors of hydrostatic reduction failure (p < 0.05).
Main Results:
- A high failure rate (83.9%) was observed for hydrostatic reduction in 56 pediatric patients.
- Age, sex, symptom onset, and intussusception location were not significant predictors of failure.
- Dehydration emerged as the sole significant risk factor, increasing failure odds by 16.80 (p = 0.001).
Conclusions:
- Dehydration is a critical factor predicting hydrostatic reduction failure in pediatric intussusception.
- This finding highlights the importance of assessing hydration status when considering non-operative management.
- Further research may explore interventions to mitigate dehydration-related failure risks.
Introduction:
Intussusception is a medical emergency caused by proximal insertion of the intestinal segment to its lumen, which results in ischemia, necrosis, and sepsisassociated mortality in pediatric patients. Intussusception is managed mainly by surgical reduction; hydrostatic reduction is a noninvasive alternative with lower risk of complications. The study was aimed to analyze the risk factors for the failure of hydrostatic reduction in children with intussusception at the Hasan Sadikin General Hospital.
Materials And Methods:
The medical records of children diagnosed with intussusception and treated with hydrostatic reduction during January 2010 and September 2019 were included. Variables of the study included age, sex, onset of symptoms, and outcome. Logistic regression analyses were performed to determine the significance and strength of correlation on the included characteristics with outcomes of hydrostatic reduction in the population. The p < 0.05 was deemed significant.
Results:
There were a total of 56 children with intussusception who were treated with hydrostatic therapy during the study period. The failure rate of hydrostatic therapy was 83.9%. Age, sex, onset of symptoms, and location of intussusception were not significantly associated with the failure of hydrostatic reduction (p > 0.05). Dehydration was the only symptom significantly associated with the failure of hydrostatic reduction (OR 16.80; p = 0.001).
Conclusion:
Dehydration is significantly associated with the failure of hydrostatic reduction in children with intussusception.
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