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Asthma and smoking: A review
Audrey Kamga1, Cécile Rochefort-Morel2, Yannick Le Guen3
1Inserm, Univ Brest, CHRU Brest, UMR 1304, GETBO, Brest, France.
Respiratory Medicine and Research
|July 28, 2022
Summary
Active smokers with asthma experience more severe symptoms and poorer treatment response, despite similar prevalence. Smoking complicates asthma management and hinders cessation efforts due to nicotine dependence.
Area of Science:
- Pulmonology
- Respiratory Medicine
- Clinical Research
Background:
- Asthma is frequently linked to cigarette smoking, yet active smokers are often excluded from clinical trials.
- The prevalence of smoking-associated asthma is comparable to general asthma populations.
- Asthma in active smokers is typically more severe and challenging to manage.
Conclusions:
- Active smoking significantly worsens asthma management and prognosis.
- Understanding the mechanisms of poor ICS response is crucial for developing targeted therapies.
- Addressing nicotine dependence is vital for successful smoking cessation in asthmatic individuals.
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