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Simple, Skin-Attachable, and Multifunctional Colorimetric Sweat Sensor.

Xiaoping Yue1, Feiyang Xu1, Linrong Zhang1

  • 1Institute of Advanced Materials (IAM) and Key Laboratory of Flexible Electronics (KLoFE), Nanjing Tech University (Nanjing Tech), 30 South Puzhu Road, Nanjing 211816, P. R. China.

ACS Sensors
|July 29, 2022
PubMed
Summary

A novel, flexible sweat sensor offers a simple, noninvasive method for early illness detection. This cost-effective device analyzes multiple sweat components, enabling convenient health monitoring at home.

Keywords:
colorimetricmicrofluidicmultiplex analysissweat sensorwearable sensor

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Area of Science:

  • Biomedical Engineering
  • Wearable Technology
  • Point-of-Care Diagnostics

Background:

  • In situ sweat analysis offers a noninvasive, convenient, and cost-effective method for early illness detection.
  • Existing methods may lack the multiplexed analysis capabilities required for comprehensive health monitoring.
  • Wearable sensors are crucial for continuous and accessible physiological data collection.

Purpose of the Study:

  • To develop a flexible, skin-attachable colorimetric sweat sensor for simultaneous multiplexed analysis.
  • To enable early diagnosis of physical illness through simple and convenient sweat monitoring.
  • To create a cost-effective and easily fabricated sensor for potential commercialization.

Main Methods:

  • Fabrication of a flexible, skin-attachable colorimetric sweat sensor.
  • Simultaneous detection of glucose, lactate, urea, and pH in sweat.
  • Integration of sweat loss and skin temperature measurement capabilities.
  • Utilizing naked-eye or smartphone readout for convenience.

Main Results:

  • The sensor successfully performed multiplexed analysis of key sweat biomarkers.
  • Only 2.5 μL of sweat was required for comprehensive testing.
  • Results for sweat loss and chemical sensing were conveniently readable.
  • Body temperature detection was achievable with an additional electrical circuit.

Conclusions:

  • The developed sweat sensor provides a novel, cost-effective, and convenient approach for in vitro diagnosis of multiple sweat components.
  • The sensor's ease of fabrication and cost-effectiveness indicate strong potential for commercialization.
  • This technology advances noninvasive health monitoring for family care and early illness detection.