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Vaccinations

Vaccinations

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Immunological Memory

Immunological Memory

Immunological memory, a pivotal pillar of the adaptive immune system, is responsible for the body's ability to remember and respond more swiftly and effectively to previously encountered pathogens. This remarkable feature is what makes vaccines so effective in preventing diseases.
What is Immunological Memory?
Immunological memory is an integral function of the immune system that allows it to recognize and react more rapidly and effectively to pathogens previously encountered. This feature...

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Morphoea following COVID-19 vaccination.

Dawn Ai Qun Oh¹, Shang-Ian Tee¹, Yee Kiat Heng¹

¹National Skin Centre, Singapore City, Singapore.

Clinical and Experimental Dermatology

|July 29, 2022

Summary

Generalized morphoea developed in a patient following COVID-19 mRNA vaccination. This case highlights a potential, though rare, adverse reaction to the vaccine, prompting investigation into underlying mechanisms.

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Area of Science:

Dermatology
Immunology
Vaccinology

Background:

Cutaneous adverse events following vaccination are increasingly reported.
Morphoea is a localized sclerosing skin condition with autoimmune associations.

Observation:

A patient developed generalized morphoea shortly after receiving a COVID-19 mRNA vaccine.
The onset of skin lesions was temporally associated with the vaccination event.

Findings:

The case suggests a possible link between COVID-19 mRNA vaccination and the development of generalized morphoea.
Potential pathomechanisms involving immune dysregulation triggered by the vaccine are discussed.

Implications:

This case adds to the spectrum of rare dermatological side effects associated with mRNA vaccines.
Further research is needed to elucidate the precise immunopathological pathways.
Clinicians should be aware of this potential association when evaluating patients with new-onset morphoea post-vaccination.