[Diagnostic problems in disorders of thrombocyte functions]

Numerous specific methods have been introduced lately in the clinical practice allowing the determination of the exact defect in platelet functions of the patient. Those methods are divided in five groups: global methods in vivo and in vitro, methods reflecting the platelet adhesiveness, platelet aggregation, platelet secretion, platelet participation in coagulation. The author is one of the first that introduced the study on platelet aggregation and secretion by aggregometer as well as the study of factor VIII antigen and von Willebrand factor. The author, based on his experience, proposes a diagnostic constellation of tests for establishing the nature of platelet defect.