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Prolonged Computer Use by Office Workers Induces Ocular Symptoms Associated With Tear Film Alterations and
Alejandra Saavedra Morales1, Cesar Antonio González Díaz, Guadalupe Cleva Villanueva López
1From the Escuela Nacional de Medicina y Homeopatía, Instituto Politécnico Nacional, Ciudad de México, México (Saavedra Morales); Escuela Superior de Medicina, Instituto Politécnico Nacional, Ciudad de México, México (González Díaz, Villanueva López, Sánchez Monroy); Universidad Nacional Autónoma de México, Facultad de Estudios Superiores Cuautitlán Izcalli, Estado de México, México (Padilla Juárez); and Centro Interdisciplinario de Ciencias de la Salud Unidad Santo Tómas, Instituto Politécnico Nacional, Ciudad de México, México (Luna Torres).
Objective:
The aim of the study was to evaluate office workers for symptoms of computer vision syndrome (CVS) and alterations in the tear film relate to the hours of daily computer use.
Methods:
Sixty-seven volunteers were divided into 2 groups: 2 to 6 and 7 to 12 hours of daily computer use. Computer vision syndrome symptoms, tear film stability by tear film break-up time test, and composition of mucin 5 AC, catalase, and IL-6 was assessed by relative gene expression of conjunctival impression cytology samples were examined.
Results:
All participants exhibited moderate symptoms of CVS, whereas 90% showed reduced tear film stability. For the 7- to 12-hour (vs 2- to 6-hour) group, these effects were more pronounced and overexpression of mucin 5 AC and catalase was detected.
Conclusions:
Prolonged computer use induced an overexpression of mucin 5 AC and catalase and instability of the tear film, associated with ocular symptoms.
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