Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Repolarization abnormalities in mitral valve prolapse.

D G Meyers, N L Vallone, T R Engel

    American Heart Journal
    |June 1, 1987
    PubMed
    Summary
    This summary is machine-generated.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    Legibility of doctors' handwriting is as good (or bad) as everyone else's.

    Quality & safety in health care·2006
    Same author

    The iron hypothesis:does iron play a role in atherosclerosis?

    Transfusion·2000
    Same author

    Impact of a clinical pathway on the care and costs of myocardial infarction.

    Angiology·2000
    Same author

    Treatment of multifocal atrial tachycardia by treatment of pulmonary insufficiency: or is it vice versa?

    Chest·2000
    Same author

    Possible association of a reduction in cardiovascular events with blood donation.

    Heart (British Cardiac Society)·1997
    Same author

    The usefulness of diagnostic tests on pericardial fluid.

    Chest·1997
    Same journal

    Cardiometabolic Health of Low- and Higher-Income Adults in the United States, 2009-2023.

    American heart journal·2026
    Same journal

    Moving Beyond Technical Capability to Regulatory Integration for Digital Health Technology Devices-Brief Communication from the Cardiovascular Sciences Research Consortium.

    American heart journal·2026
    Same journal

    THE SOCIETY OF CRITICAL CARE CARDIOLOGY - RATIONALE, BLUEPRINT, AND LESSONS LEARNED IN THE CREATION OF A NEW MULTIDISCIPLINARY PROFESSIONAL ORGANIZATION.

    American heart journal·2026
    Same journal

    DOAC Score Among Patients Receiving Vitamin K Antagonists.

    American heart journal·2026
    Same journal

    Considerations for Using Atrial Fibrillation Burden as a Surrogate Endpoint A Report from the Cardiovascular Sciences Research Consortium.

    American heart journal·2026
    Same journal

    Prognostic Impact of Combined Inflammatory Markers in Patients Undergoing Percutaneous Coronary Intervention.

    American heart journal·2026
    See all related articles

    Electrocardiogram (ECG) abnormalities like ST-T changes and QT prolongation are common in mitral valve prolapse (MVP) patients. However, these ECG findings do not reliably predict symptoms or complications in individuals with MVP.

    Area of Science:

    • Cardiology
    • Clinical Electrophysiology
    • Echocardiography

    Background:

    • Inferolateral ST depression, T wave inversion, and QT prolongation are ECG findings often reported in symptomatic mitral valve prolapse (MVP) patients.
    • A recent population-based survey noted these ECG changes were less common in asymptomatic MVP subjects.
    • The clinical significance of these ECG findings in relation to symptoms and hemodynamic sequelae in MVP remains unclear.

    Purpose of the Study:

    • To investigate the relationship between specific ECG changes (ST-T abnormalities, QT prolongation) and clinical presentation in patients with mitral valve prolapse (MVP).
    • To determine if these ECG findings correlate with symptoms, physical examination findings, or hemodynamic consequences of MVP.
    • To assess the utility of ECG abnormalities in identifying clinically relevant subsets of MVP patients.

    Related Experiment Videos

    Main Methods:

    • Retrospective review of electrocardiograms (ECGs) from 119 patients diagnosed with MVP via echocardiography.
    • Patients ranged in age from 18 to 60 years.
    • Correlation of ECG findings with patient symptoms, physical exam findings (apical systolic murmurs), and echocardiographic evidence of mitral regurgitation or left atrial enlargement.

    Main Results:

    • ST-T wave abnormalities were observed with similar frequency in both symptomatic (27%) and asymptomatic (29%) MVP patients.
    • QT prolongation was more frequent in symptomatic patients (25%) compared to asymptomatic ones (10%), but did not predict syncope.
    • Neither ST-T changes nor QT prolongation were useful in identifying patients with hemodynamic sequelae such as mitral regurgitation or left atrial enlargement.

    Conclusions:

    • While ST-T changes and QT prolongation are frequent in mitral valve prolapse (MVP) patients compared to the general population, they are not specific.
    • These ECG abnormalities do not reliably identify symptomatic patients or those with significant hemodynamic sequelae.
    • The routine use of these ECG findings for risk stratification or subset identification in MVP patients is not supported by this study.