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ARMS/Kidins220 regulates nociception by controlling brain-derived neurotrophic factor secretion

Julia Sánchez-Sánchez1,2, Cristina Vicente-García1,2, Daniel Cañada-García1,2

  • 1Department of Cell Biology and Pathology, Instituto de Neurociencias de Castilla y León (INCyL), Universidad de Salamanca, Salamanca, Spain.

Pain
|August 2, 2022
PubMed
Summary

The scaffold protein ARMS/Kidins220 modulates pain by regulating nerve growth factor (NGF)/TrkA signaling. Reduced ARMS/Kidins220 enhances brain-derived neurotrophic factor (BDNF) secretion, impacting nociception.

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