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Related Concept Videos

Menopause01:28

Menopause

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Menopause, a natural biological process marking the end of a woman's fertility, typically occurs between the fifth and sixth decade of life. This phase is characterized by the exhaustion of the ovarian follicle pool, leading to less responsive ovaries despite the high levels of Follicle Stimulating Hormone (FSH) and Luteinizing Hormone (LH). The consequential decrease in estrogen production results in symptoms like hot flashes, heavy sweating, headaches, hair loss, muscle pains, vaginal...
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Hormonal Regulation of the Menstrual Cycle01:22

Hormonal Regulation of the Menstrual Cycle

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The ovarian cycle regulates endometrial changes throughout a single menstrual cycle via the coordinated action of gonadotrophin-releasing hormone (GnRH) and gonadotrophins.
At puberty, GnRH begins a pulsatile release pattern, which triggers the anterior pituitary gland to secrete follicle-stimulating hormone (FSH) and luteinizing hormone (LH). The frequency and amplitude of GnRH pulses vary across the menstrual cycle, with faster pulses favoring LH release and slower pulses favoring FSH...
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The Menstrual Cycle01:19

The Menstrual Cycle

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The menstrual cycle is a recurrent sequence of changes in the uterine endometrium, specifically its functional layer, the stratum functionalis. This cycle prepares the uterus for potential pregnancy. This cycle typically spans 21–35 days, averaging 28 days, and aligns with the ovarian cycle, regulated by fluctuating levels of ovarian hormones, primarily estrogen and progesterone.
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Hormonal Control of the Ovarian Cycle01:30

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The ovarian cycle is meticulously regulated by the hypothalamic-pituitary-gonadal axis. This cycle orchestrates the release of a mature oocyte, essential for reproduction.
Before puberty, the hypothalamus releases GnRH in a low frequency, low amplitude pulsatile manner. This along with the immature hypothalamic-pituitary-gonadal axis activity, results in low estrogen levels and the absence of a fully functional ovarian cycle.  At puberty, GnRH secretion increases in both frequency and...
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Oogenesis02:07

Oogenesis

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In human women, oogenesis produces one mature egg cell or ovum for every precursor cell that enters meiosis. This process differs in two unique ways from the equivalent procedure of spermatogenesis in males. First, meiotic divisions during oogenesis are asymmetric, meaning that a large oocyte (containing most of the cytoplasm) and minor polar body are produced as a result of meiosis I, and again following meiosis II. Since only oocytes will go on to form embryos if fertilized, this unequal...
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Menses Phase01:18

Menses Phase

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The uterine cycle begins with the menstrual phase, which is considered day one of the cycle and typically lasts about five days. This phase is characterized by the degeneration and shedding of the stratum functionalis, the functional layer of the endometrium.
When fertilization does not occur, the corpus luteum deteriorates, causing a significant drop in the levels of estrogen and progesterone in the body. This hormonal decrease triggers the release of prostaglandins, which cause the uterine...
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#Menopause: the menopause ontology project.

Elissa Trieu1, Abigail P Davenport1, Sheryl A Kingsberg2

  • 1From the MedStar Washington Hospital Center, Georgetown University, Washington, DC.

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Summary

This study created the first hashtag ontology for menopause, identifying 32 key terms. Standardizing menopause-related hashtags can improve communication between healthcare providers and patients online.

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Area of Science:

  • Social Media Analysis
  • Health Communication
  • Ontology Development

Background:

  • Social media platforms are increasingly used by patients and healthcare professionals for health-related discussions.
  • Effective communication regarding menopause on social media is crucial for patient support and education.
  • A standardized framework for menopause-related hashtags is lacking.

Purpose of the Study:

  • To develop a comprehensive hashtag ontology specifically for the topic of menopause.
  • To organize and categorize hashtags used in online discussions about menopause.
  • To facilitate standardized terminology for improved digital health communication.

Main Methods:

  • Analysis of tweets containing the #menopause hashtag from November 2019 to November 2021.
  • Inclusion of tweets from societies, expert influencers, and "Top" tweets for comprehensive hashtag identification.
  • Review and refinement of identified hashtags by social media influencers and experts, followed by subject-based grouping.

Main Results:

  • Analysis of 382 tweets identified 123 unique hashtags.
  • The final ontology includes 32 standardized hashtags.
  • Hashtags were categorized into: general, premature menopause, hormones, sexual function, and genital disorders.

Conclusions:

  • This study presents the first hashtag ontology tailored to menopause.
  • Standardized terminology through a menopause hashtag ontology can enhance communication among medical professionals and with patients.
  • Adoption of this ontology can improve the organization and accessibility of menopause information shared on social media.