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Presumptive metastatic leiomyosarcoma in a feedlot steer
Fernando J Guardado1, Kamal Gabadage1, Andrew L Allen1
1Department of Large Animal Clinical Sciences (Guardado, Gabadage) and Department of Veterinary Pathology (Allen), Western College of Veterinary Medicine, University of Saskatchewan, 52 Campus Drive, Saskatoon, Saskatchewan.
Summary
A rare leiomyosarcoma, a type of cancer, was diagnosed in a feedlot steer. This case highlights diagnostic challenges in large animal veterinary medicine, especially in adverse conditions.
Area of Science:
- Veterinary Pathology
- Animal Oncology
Background:
- Leiomyosarcomas are uncommon neoplasms in cattle, particularly in North America.
- This case involves a 14-month-old feedlot steer presenting with clinical signs of depression.
Observation:
- Post-mortem examination revealed extensive abdominal and thoracic masses, including a liver mass eroding into the vena cava.
- Pulmonary metastases suggested hematogenous spread of the neoplasm.
Findings:
- Histologic examination confirmed neoplasia, with immunohistochemistry supporting a diagnosis of leiomyosarcoma.
- The primary tumor was suspected to originate from the vena cava within the liver.
Implications:
- This case contributes valuable data to the limited understanding of bovine leiomyosarcomas.
- It underscores the difficulties veterinarians face during field necropsies in extreme temperatures and emphasizes diagnostic techniques for rare diseases.

