Gastric defect closure after endoscopic full-thickness resection: the closing while dissecting technique.
Haibo Sun1, Tingting Cao1, Fan Zhang1
1Department of Gastroenterology and Endoscopy Center, The First Hospital of Jilin University, 71 Xinmin Street, Changchun, Jilin, 130021, China.
Surgical Endoscopy
|August 3, 2022
Summary
This study demonstrates a new endoscopic technique for closing gastric defects after full-thickness resection (EFTR). The "close while dissecting" method using endoclips proved safe and effective for gastric submucosal tumors.
Area of Science:
- Gastroenterology
- Endoscopic Surgery
- Oncology
Background:
- Complete closure of gastric wall defects is crucial after endoscopic full-thickness resection (EFTR).
- A novel endoscopic technique,
- closing while dissecting
- , was developed to address this need.
Purpose of the Study:
- To evaluate the efficacy, safety, and clinical outcomes of the
- interrupted-close during dissection
- technique for gastric defect closure post-EFTR.
Main Methods:
- Retrospective analysis of 27 patients undergoing EFTR between January 2020 and March 2021.
- Gastric defects were closed using the
- interrupted-close during dissection
- technique with endoclips.
- Evaluation of tumor characteristics, en bloc resection rates, and postoperative adverse events.
Main Results:
- Successful en bloc resection of all submucosal tumors (mean diameter 1.3 cm), including GISTs, leiomyomas, and schwannomas.
- No instances of hemorrhage, peritonitis, or delayed perforation.
- All wounds healed within 3 months, with no observed tumor recurrence during a mean 8.5-month follow-up.
Conclusions:
- The
- interrupted-close during dissection
- approach is feasible and safe for EFTR of gastric submucosal tumors.
- This technique facilitates effective closure of gastric wall defects, supporting clinical application.


