Psychometric Properties of the Mini Pediatric Asthma Quality of Life Questionnaire in a US Sample

The 13-item Mini Pediatric Asthma Quality of Life Questionnaire (MiniPAQLQ) was developed to measure asthma-specific quality of life in children. However, no validation studies have been conducted in the United States. This study aimed at determining the psychometric properties of the MiniPAQLQ in a US sample. Children aged 7-17 years and with an asthma diagnosis (n = 193) were identified from primary care clinics within an integrated healthcare system in the Southeastern United States. Participants completed surveys consisting of the MiniPAQLQ and the control module of the Asthma Therapy Assessment Questionnaire (ATAQ). Convergent validity was determined based on association between the MiniPAQLQ and ATAQ scores. Internal consistency reliability was determined from Cronbach's alpha coefficients for the MiniPAQLQ subscales (symptoms, emotions, and activities). Item-convergent validity was examined based on corrected item-total correlations. Item-discriminant validity was determined by comparing corrected item-total correlations and item-to-other-scale correlations. Floor and ceiling effects were examined based on the percentage of respondents having the lowest and highest scores on the MiniPAQLQ. A negative association was observed between quality of life scores from the MiniPAQLQ and asthma control as determined from the ATAQ, providing evidence of convergent validity. Internal consistency reliability was good with Cronbach's alpha values of above 0.8 for the MiniPAQLQ subscales. Item-convergent validity was confirmed, whereas item-discriminant validity was not confirmed. Floor effects were absent, whereas ceiling effects were present. The MiniPAQLQ possesses moderately good psychometric properties among children and adolescents in the United States and could be a useful tool for asthma management in clinical practice.