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Related Concept Videos

Pulmonary Tuberculosis I01:29

Pulmonary Tuberculosis I

305
Tuberculosis, often called TB, is a contagious illness primarily caused by Mycobacterium tuberculosis. It mainly affects the lung parenchyma but can also impact other body parts.
Causative Organism
The primary infectious agent causing tuberculosis is Mycobacterium tuberculosis, a slow-growing, acid-fast, aerobic rod that exhibits sensitivity to heat and ultraviolet light. Instances of Mycobacterium bovis and Mycobacterium avium contributing to the development of TB infection are rare.
Mode of...
305
Pulmonary Tuberculosis IV01:26

Pulmonary Tuberculosis IV

190
Tuberculosis, more commonly referred to as TB, is an infectious disease stemming from Mycobacterium tuberculosis. While it primarily impacts the lungs, TB can also affect other body areas. Given its severity and global impact, timely and accurate diagnosis is crucial for controlling its spread and improving patient outcomes.
Several diagnostic approaches are used to detect TB. The conventional method is the Tuberculin Skin Test (TST), also known as the Mantoux test. However, this method has...
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Pulmonary Tuberculosis V01:28

Pulmonary Tuberculosis V

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Medical management of tuberculosis (TB) patients involves a comprehensive approach that includes diagnosis, treatment, and monitoring. The specific strategies can vary depending on the type of tuberculosis (latent or active), the patient's overall health status, and other considerations.
Latent tuberculosis infection occurs when TB bacteria are present in a person's body, but are not causing illness or symptoms. It is not contagious, and preventive treatment is crucial to avoid the...
229
Pulmonary Tuberculosis II01:28

Pulmonary Tuberculosis II

321
Tuberculosis, or TB, is a bacterial infectious disease caused by Mycobacterium tuberculosis. While its primary impact is on the lungs, leading to pulmonary tuberculosis, it can also affect various other organs, a condition referred to as extrapulmonary tuberculosis.
Here is a detailed explanation of its pathophysiology:
Transmission: The process begins when a person inhales droplet nuclei containing M. tuberculosis. These are typically released into the air when an individual with pulmonary or...
321
Pulmonary Tuberculosis III01:31

Pulmonary Tuberculosis III

419
Tuberculosis (TB) is a contagious infection primarily affecting the lung parenchyma but which can also affect other body parts. TB can be classified based on disease development, presentation, and the affected anatomical site.
The first classification is based on the development of the disease, and it includes the following categories:
419
Pulmonary Embolism II: Diagnostic Studies and Interprofessional Care01:29

Pulmonary Embolism II: Diagnostic Studies and Interprofessional Care

40
Diagnosing Pulmonary EmbolismDiagnosing pulmonary embolism (PE) involves clinical assessment and advanced imaging tests. The preferred diagnostic tool is the spiral (helical) CT scan or CT angiography (CTA), which uses intravenous contrast media to visualize the pulmonary vasculature and identify emboli.A ventilation-perfusion (V/Q) scan is an alternative for patients unable to receive contrast media. This scan includes both perfusion and ventilation scanning. Perfusion scanning involves...
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Related Experiment Video

Updated: Sep 2, 2025

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Pulmonary Tuberculosis-Related Ischemic Stroke: A Retrospective Case Control Study.

Yunfei Wei1,2, Shiting Tang1, Zhouhua Xie3

  • 1Department of Neurology, The First Affiliated Hospital of Guangxi Medical University, Guangxi Key Laboratory of Precision Medicine in Cardio-cerebrovascular Diseases Control and Prevention & Guangxi Clinical Research Center for Cardio-cerebrovascular Diseases, Nanning, People's Republic of China.

Journal of Inflammation Research
|August 4, 2022
PubMed
Summary

Pulmonary tuberculosis-related ischemic stroke (TBRIS) often occurs within three months of tuberculosis diagnosis. Key risk factors include elevated inflammatory markers and platelet activation, suggesting an intensive immune response contributes to stroke development.

Keywords:
independent risk factorischemic strokepathogenesispulmonary tuberculosistuberculosis-related ischemic stroke

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Area of Science:

  • Neurology
  • Infectious Diseases
  • Hematology

Background:

  • Ischemic stroke in pulmonary tuberculosis (pTB) patients is understudied.
  • Understanding the clinical features and pathogenesis of tuberculosis-related ischemic stroke (TBRIS) is crucial.

Purpose of the Study:

  • To explore the clinical features of TBRIS.
  • To investigate the underlying pathogenesis of TBRIS.

Main Methods:

  • Retrospective study comparing TBRIS patients with a control pTB group.
  • Clinical data collection and multiple logistic regression analysis to identify risk factors.

Main Results:

  • 179 TBRIS and 179 pTB patients were analyzed.
  • 56.42% of TBRIS events occurred within 3 months of pTB diagnosis.
  • Independent risk factors for TBRIS included increased mean platelet volume, elevated D-dimer, C-reactive protein, serum ferritin, and monocyte percentage.

Conclusions:

  • TBRIS commonly presents within 3 months of pTB diagnosis.
  • Intensive immune response to tuberculosis may drive platelet activation and hypercoagulability, leading to TBRIS.
  • A TBRIS index (0.3234) may aid in identifying at-risk pTB patients for preventive measures, pending further validation.