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Risk Factors of Cardiovascular Pathology in Patients with Gout
Lidiya Khituova1, Venera Khabizhanova2, Abdugani Musayev3
1Department of Child Diseases, Kazakh National Medical University Named after S. Asfendiyarov, Kazakhstan.
Insights
Patients with gout frequently have high cardiovascular disease risk factors like elevated BMI and dyslipidemia. This highlights the critical need to manage these risks to prevent serious cardiac events in this population.
Area of Science:
- Rheumatology and Cardiology
- Metabolic Disorders Research
Background:
- Gout is linked to metabolic disturbances and cardiovascular diseases (CVD).
- High mortality in gout patients is associated with numerous risk factors and comorbidities.
Purpose of the Study:
- To determine the frequency of cardiovascular disease risk factors in gout patients.
- To assess the overall cardiovascular disease risk in individuals with gout.
Main Methods:
- Retrospective study of 218 gout patients (S.L. Wallace criteria).
- Cardiovascular risk calculated using the SCORE scale for major coronary events.
Main Results:
- Prevalence of arterial hypertension and BMI > 25 kg/m² (90.8%).
- High rates of dyslipidemia: elevated total cholesterol (63.8%), low HDL (71.6%), hypertriglyceridemia (60.5%).
- 80.3% of patients exhibited high cardiovascular risk (>5%); 19.7% had low/medium risk (1-4%).
Conclusions:
- Increased BMI (>25 kg/m²) and dyslipidemia are the most common risk factors in gout patients.
- A significant proportion of gout patients are at elevated risk for cardiovascular pathology.
Objective:
To determine the frequency and assess the risk of cardiovascular disease in patients suffering from gout.
Background:
Gout is a sign of disturbed metabolism, which is associated with cardiovascular diseases (CVD). Soaring mortality is associated with a lot of risk factors and comorbid conditions, which have to be dealt with the help of scientists and practitioners.
Methods:
The following retrospective study included 218 patients suffering from gout according to the criteria of S.L. Wallace. The risk of major coronary events was calculated via the SCORE scale.
Results:
Arterial hypertension and BMI > 25 kg / m2 (90.8%) have prevailed among the respondents. Increased level of total cholesterol (TC) was detected in 63.8% cases, decreased level of highdensity lipoproteins - in 71.6%, and hypertriglyceridemia - in 60.5% relevantly. 175 patients (80.3%) had high cardiovascular risk (estimated more than 5%). 43 (19.7%) of them had a low and medium risk of developing fatal CVD (1-4%). The high share of patients suffering from gout was endangered with cardiovascular pathology.
Conclusion:
The most frequently matched risk factors among patients suffering from gout are an increase in BMI> 25 kg/m2 (90.8%) and dyslipidemia.
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