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Related Concept Videos

Nonlinear Pharmacokinetics: Drug Elimination for IV Bolus Injection00:59

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In pharmacokinetics, the elimination rate of a drug following a capacity-limited model is primarily controlled by two parameters: Vmax and KM. These parameters are crucial in how the drug behaves inside the body after administration.
Following the administration of a single intravenous (IV) bolus injection, we can determine the concentration of the drug in the plasma at any given time. This calculation is achieved using a specific equation that integrates the values of Vmax and KM.
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Intravenous (IV) infusion is often utilized when continuous and controlled drug delivery is necessary, such as during surgery or in the treatment of chronic diseases. This method offers numerous advantages, including immediate drug action, precise control over dosage, and bypassing the first-pass metabolism.
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Sustained Reduction in Intravenous Pump Turnaround Time Using Lean Methodology.

Smriti Neogi1, Glenn Schneider2, Joshua K Schaffzin3,4

  • 1James M. Anderson Center for Health Systems Excellence, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio.

Pediatric Quality & Safety
|August 5, 2022
PubMed
Summary
This summary is machine-generated.

Lean methodology significantly improved intravenous (IV) pump repair efficiency. This process reduced device turnaround time by 89%, ensuring timely availability of essential medical equipment.

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Area of Science:

  • Healthcare Operations
  • Biomedical Engineering
  • Process Improvement

Background:

  • Intravenous (IV) pumps are critical for delivering life-sustaining medications.
  • Inefficiencies in IV pump repair processes increase costs and delay equipment availability.
  • Prompt access to functional IV pumps is essential for patient care.

Purpose of the Study:

  • To identify and address inefficiencies in the IV pump management and repair process.
  • To implement Lean methodology to reduce device turnaround time (TAT).
  • To evaluate the sustainability of implemented improvements.

Main Methods:

  • A 60-day before-after trial using the Toyota Production System Lean methodology.
  • Value stream mapping and manual time studies to identify bottlenecks.
  • Interventions included improving repair request tracking, workroom organization, parts inventory, and delivery systems.

Main Results:

  • Mean IV pump TAT reduced by 89%.
  • Sustained TAT improvements of 74%-97% below baseline for 4 years.
  • Improvements maintained even during the COVID-19 pandemic.

Conclusions:

  • Lean methodology effectively created a system for prompt delivery of safe, functional IV pumps.
  • The implemented system is sustainable and can be adopted by various healthcare professionals.
  • Process optimization enhances the availability of essential medical equipment.