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25-OH Vitamin D concentrations measured by LC-MS/MS are equivalent in serum and EDTA plasma
Lisa N van der Vorm1, Caroline Le Goff2, Stéphanie Peeters2
1Department of Clinical Chemistry, Central Diagnostic Laboratory, Amsterdam University Medical Center, Amsterdam, the Netherlands.
Abstract:
In contrast to a recent study reporting an unexpected significant difference for total 25-hydroxyvitamin D (25(OH)D) between serum and EDTA plasma, we demonstrate that concentrations of total 25(OH)D, 25(OH)D2, 25(OH)D3 and 24,25(OH)2D3 do not differ between matched serum and EDTA plasma samples, using two well-characterized LC-MS/MS methods.
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