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Updated: Sep 2, 2025

Generic Protocol for Optimization of Heterologous Protein Production Using Automated Microbioreactor Technology
Published on: December 15, 2017
Advances in microbial production of feed amino acid
Kuo Zhao1, Jianmin Liu2, Cong Gao1
1State Key Laboratory of Food Science and Technology, Jiangnan University, Wuxi, China; International Joint Laboratory on Food Safety, Jiangnan University, Wuxi, China.
Abstract:
Feed amino acids have numerous applications, and the market demand for them is likely to grow. Microbial cell factories promise the sustainable production of feed amino acids; however, their performance is significantly affected by the availability of precursors, carbon metabolic flux, and transporter systems. To circumvent these potential roadblocks, high-performance microbial cell factories have been constructed by strengthening the supply of precursors, increasing metabolic pathway flux, and engineering transporters. In this review, limiting factors and recent technical advances affecting the production of feed amino acids in microbial cell factories are discussed. In addition, existing challenges and potential strategies for increasing the output of these amino acids are described.
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