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After cellular or tissue damage, the resident stem cells present in the human body can locally repair and regenerate the damaged tissue or organ. However, even though some tissues do not have stem cells, they can repair and regenerate with the help of pre-existing cells. For example, beta cells of the pancreas and hepatocytes of the liver can divide to renew and regenerate the tissue. Here, both cell division and cell death are well regulated by homeostasis.
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The skin is divided into epidermis, dermis, and hypodermis, the skin's outermost, middle, and inner layers. The human epidermal layer regularly undergoes renewal, where old, dead cells are replaced by new cells. Epidermal stem cells or EpiSCs divide and differentiate to restore the lost cells. For the renewal process, some EpiSCs continuously self-renew. In contrast, few others differentiate into transit-amplifying cells, which later form prickle or spinous cells, followed by granular...
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Noninvasive Hair Rejuvenation.

Jordan Sand1, Scott Walen2

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PubMed
Summary
This summary is machine-generated.

Providers worldwide increasingly use surgical and nonsurgical hair loss treatments. Gender influences treatment decisions for androgenetic alopecia, with options like minoxidil, finasteride, and promising platelet-rich plasma injections.

Keywords:
Androgenetic alopeciaHair rejuvenationMedical therapyPlatelet-rich plasma

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Area of Science:

  • Dermatology and Trichology
  • Medical Treatments for Hair Loss

Background:

  • Hair loss affects both men and women globally.
  • Pathophysiology of hair loss may differ between sexes, influencing treatment strategies.

Purpose of the Study:

  • To review current nonsurgical and surgical hair loss treatments.
  • To highlight gender-specific considerations in hair loss management.
  • To discuss the role of emerging therapies like platelet-rich plasma.

Main Methods:

  • Review of Food and Drug Administration-approved treatments.
  • Analysis of treatment modalities for androgenetic alopecia.
  • Inclusion of emerging therapies such as platelet-rich plasma injections.

Main Results:

  • Three FDA-approved nonsurgical treatments for androgenetic alopecia exist: minoxidil, finasteride, and low-light laser therapy.
  • Platelet-rich plasma injections show potential as a standalone or adjunctive therapy.

Conclusions:

  • Gender is a crucial factor in selecting hair loss treatments.
  • Platelet-rich plasma is a promising addition to the therapeutic landscape for androgenetic alopecia.