Related Experiment Video
Updated: Sep 2, 2025

Colorectal Cancer Cell Surface Protein Profiling Using an Antibody Microarray and Fluorescence Multiplexing
Published on: September 25, 2011
Positive-gradient-weighted object activation mapping: visual explanation of object detector towards precise
Hayato Itoh1, Masashi Misawa2, Yuichi Mori2,3
1Graduate School of Informatics, Nagoya University, Furo-cho, Chikusa-ku, Nagoya, 464-8601, Japan. hitoh@mori.m.is.nagoya-u.ac.jp.
Purpose:
Precise polyp detection and localisation are essential for colonoscopy diagnosis. Statistical machine learning with a large-scale data set can contribute to the construction of a computer-aided diagnosis system for the prevention of overlooking and miss-localisation of a polyp in colonoscopy. We propose new visual explaining methods for a well-trained object detector, which achieves fast and accurate polyp detection with a bounding box towards a precise automated polyp localisation.
Method:
We refine gradient-weighted class activation mapping for more accurate highlighting of important patterns in processing a convolutional neural network. Extending the refined mapping into multiscaled processing, we define object activation mapping that highlights important object patterns in an image for a detection task. Finally, we define polyp activation mapping to achieve precise polyp localisation by integrating adaptive local thresholding into object activation mapping. We experimentally evaluate the proposed visual explaining methods with four publicly available databases.
Results:
The refined mapping visualises important patterns in each convolutional layer more accurately than the original gradient-weighted class activation mapping. The object activation mapping clearly visualises important patterns in colonoscopic images for polyp detection. The polyp activation mapping localises the detected polyps in ETIS-Larib, CVC-Clinic and Kvasir-SEG database with mean Dice scores of 0.76, 0.72 and 0.72, respectively.
Conclusions:
We developed new visual explaining methods for a convolutional neural network by refining and extending gradient-weighted class activation mapping. Experimental results demonstrated the validity of the proposed methods by showing that accurate visualisation of important patterns and localisation of polyps in a colonoscopic image. The proposed visual explaining methods are useful for the interpreting and applying a trained polyp detector.
More Related Videos
06:05Author Spotlight: Multiplex Immunofluorescence Combined with Spatial Image Analysis for the Clinical and Biological Assessment of the Tumor Microenvironment
Published on: June 2, 2023
12:24Computed Tomography-guided Time-domain Diffuse Fluorescence Tomography in Small Animals for Localization of Cancer Biomarkers
Published on: July 17, 2012