Related Experiment Video
Updated: Sep 2, 2025

Acupoint Needle-Embedding Combined with Ironing Therapy for Postoperative Pain After Anal Surgery
Published on: June 23, 2023
Opioid Sparing Analgesics in Spine Surgery
Logan A Reed1, Mihir Patel1, Kevin Luque1
1Department of Orthopaedic Surgery, University of Alabama at Birmingham, Birmingham, AL, USA.
Nonopioid analgesics can reduce postoperative pain and opioid use in spine surgery. This review explores various opioid-sparing options to aid surgeons in managing pain and improving patient recovery.
Area of Science:
- Anesthesiology
- Orthopedics
- Pharmacology
Background:
- Postoperative pain management often relies on opioids, leading to potential adverse effects and dependence.
- Nonopioid analgesics offer alternatives for pain control, but their implementation in spine surgery is complex.
- Standardization of nonopioid analgesic protocols is needed to optimize outcomes in spine surgery.
Purpose of the Study:
- To review the efficacy of various nonopioid analgesics for managing postoperative pain in spine surgery.
- To provide guidance for surgeons on utilizing opioid-sparing medications to reduce opioid consumption.
- To support the development of standardized pain management protocols in spine surgery.
Main Methods:
- A narrative review of published literature was conducted.
- Searches were performed using Google Scholar and PubMed.
- Keywords included "analgesics," "spine," and "pain" to identify relevant studies.
Main Results:
- Various nonopioid analgesics, including acetaminophen, NSAIDs, gabapentinoids, and ketamine, show potential for opioid sparing.
- Each nonopioid analgesic has unique advantages and disadvantages impacting universal implementation.
- Ambiguous administration guidelines present challenges for standardizing protocols in spine surgery.
Conclusions:
- Nonopioid analgesics are crucial for multimodal pain management strategies in spine surgery.
- Further research and clear guidelines are needed to optimize the use of these agents.
- Effective use of nonopioid analgesics can lead to decreased opioid reliance, faster recovery, and improved patient satisfaction.
Related Concept Videos
Opioid Analgesics: Synthetic and Semisynthetic Opioids
Local Anesthetics: Clinical Application as Spinal Anesthesia
Analgesia and Pain Management
Opioid Analgesics: Morphine and Other Natural Cogeners
Local Anesthetics: Clinical Application as Epidural Anesthesia
Since epidural anesthetics can be infused through an epidural catheter, all types of drugs, including short-acting ones, can be administered. Chloroprocaine and lidocaine are examples of short and long-duration anesthetics, respectively. Bupivacaine...
Skeletal Muscle Relaxants: Therapeutic Uses

