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Updated: Sep 2, 2025

Estimating Bilateral Atrial Function by Cardiovascular Magnetic Resonance Feature Tracking in Patients with Paroxysmal Atrial Fibrillation
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Left Atrial Dysfunction as Marker of Arrhythmic Events in Patients with Hypertrophic Cardiomyopathy

Özkan Candan1, Çetin Geçmen2, Muzaffer Kahyaoğlu2

  • 1Department of Cardiology, Faculty of Medicine, Uşak University, Uşak, Turkey.

Anatolian Journal of Cardiology
|August 9, 2022
PubMed

Insights

Peak atrial longitudinal strain, a simple measurement, can help predict appropriate Implantable Cardioverter Defibrillator (ICD) shocks in hypertrophic cardiomyopathy patients. This aids in managing high-risk individuals and preventing ventricular arrhythmias.

Area of Science:

  • Cardiology
  • Echocardiography
  • Electrophysiology

Background:

  • Hypertrophic cardiomyopathy (HCM) patients often receive Implantable Cardioverter Defibrillators (ICDs) for sudden cardiac death prevention.
  • Predicting appropriate ICD shocks remains crucial for optimizing patient management.

Purpose of the Study:

  • To evaluate if left atrial functions, assessed by speckle tracking echocardiography, predict appropriate ICD shock in HCM patients.
  • To determine the utility of classic echocardiographic and clinical parameters in predicting ICD shock.

Main Methods:

  • 87 HCM patients receiving ICDs were analyzed.
  • Left atrial functions were assessed using speckle tracking echocardiography, focusing on peak atrial longitudinal strain (PALS).
  • Clinical, electrocardiographic, and echocardiographic data were collected; patients were followed for appropriate ICD therapy.

Main Results:

  • 27.5% of patients experienced appropriate ICD therapy.
  • Decreased PALS and global longitudinal peak strain, along with higher Sudden Cardiac Death risk scores, were associated with appropriate ICD therapy.
  • PALS, Sudden Cardiac Death risk score, and global longitudinal peak strain were independent predictors of appropriate ICD therapy in high-risk patients (ESC risk score >6%).

Conclusions:

  • Peak atrial longitudinal strain is a valuable, easily measurable parameter for predicting appropriate ICD shocks in HCM patients.
  • PALS can aid in risk stratification and treatment decisions for preventing ventricular arrhythmias in high-risk ICD recipients.
Abstract

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