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Updated: Sep 2, 2025

Experimental Human Pneumococcal Carriage
Published on: February 15, 2013
Effect of Single-dose Azithromycin on Pneumococcal Carriage and Resistance: A Randomized Controlled Trial
Boubacar Coulibaly1, Dramane Kiemde1, Guillaume Zonou1
1From the Centre de Recherche en Santé de Nouna, Nouna, Burkina Faso.
Abstract:
We evaluated antibiotic resistance selection in Streptococcus pneumoniae isolates from children participating in an individually randomized trial of single-dose azithromycin versus placebo. After 14 days, the prevalence of resistance to erythromycin, oxacillin, and clindamycin was elevated in the azithromycin versus placebo group. There was no difference at 6 months.
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