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Updated: Sep 2, 2025
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Autoimmune Gastritis with a Long-term Course of Type B Gastritis: A Report of Two Cases
Takashi Ihara1, Noriko Ihara1, Ryoji Kushima2
1Ihara Clinic of Internal Medicine, Japan.
Abstract:
Autoimmune gastritis (AIG) typically exhibits the characteristics of type A gastritis and has been classified as a separate disease from type B gastritis that corresponds to Helicobacter pylori gastritis. However, many reports have suggested the involvement of H. pylori infection in the pathogenesis of AIG. In our two cases, the patients' previous gastritis exhibited a clear pattern in which H. pylori gastritis had progressed over many years, but ultimately transitioned to AIG with its spontaneous disappearance. These findings suggest that some cases of AIG might originate from long-standing H. pylori gastritis.
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