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A Semi-Quantitative Drug Affinity Responsive Target Stability DARTS assay for studying Rapamycin/mTOR interaction
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Searching for new mTOR kinase inhibitors: Analysis of binding sites and validation of docking protocols

Dorota Stary1,2,3, Eugenie Nepovimova2, Kamil Kuca2

  • 1Department of Physicochemical Drug Analysis, Faculty of Pharmacy, Jagiellonian University Medical College, Cracow, Poland.

Chemical Biology & Drug Design
|August 9, 2022
PubMed

Keywords:
ATP-binding siteFRB domaindocking validationinhibitorsmTOR kinaseprotein structure analysis

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