Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Glaucoma: Overview01:25

Glaucoma: Overview

705
Glaucoma is an eye condition characterized by increased intraocular pressure that damages the retina and optic nerve, leading to irreversible blindness if left untreated. The human eye has various components, including the cornea, iris, pupil, lens, and optic nerve. Aqueous humor is secreted by the epithelium of the ciliary body in the posterior chamber and flows through the trabecular meshwork and canal of Schlemm, maintaining normal intraocular pressure. The trabecular meshwork and the canal...
705
Open Angle Glaucoma: Treatment01:27

Open Angle Glaucoma: Treatment

534
In open-angle glaucoma, the iridocorneal angle remains open, but the trabecular meshwork becomes stiff, slowing down the outflow of aqueous humor. This causes a buildup of aqueous humor in the anterior chamber, leading to a sudden increase in intraocular pressure. The treatment for open-angle glaucoma focuses on reducing the elevated intraocular pressure by either decreasing the secretion of aqueous humor or increasing its outflow.
Drugs such as carbonic anhydrase inhibitors, α2- and...
534
Angle Closure Glaucoma: Treatment01:28

Angle Closure Glaucoma: Treatment

632
Angle-closure glaucoma, or closed-angle glaucoma, is an eye condition where the iris bulges out and blocks the iridocorneal angle, resulting in a buildup of aqueous humor and increased intraocular pressure. Immediate medical attention is necessary due to the sudden onset of symptoms. The treatment for angle-closure glaucoma includes short-term and long-term approaches. Short-term treatment involves using eye drops like pilocarpine to lower intraocular pressure by increasing aqueous humor...
632
Photoreceptors and Visual Pathways01:22

Photoreceptors and Visual Pathways

6.4K
At the molecular level, visual signals trigger transformations in photopigment molecules, resulting in changes in the photoreceptor cell's membrane potential. The photon's energy level is denoted by its wavelength, with each specific wavelength of visible light associated with a distinct color. The spectral range of visible light, classified as electromagnetic radiation, spans from 380 to 720 nm. Electromagnetic radiation wavelengths exceeding 720 nm fall under the infrared category,...
6.4K
Focusing of Light in the Eye01:16

Focusing of Light in the Eye

3.2K
Light rays enter the eye through the cornea, a transparent dome-shaped tissue that is the eye's outermost layer. The cornea bends or refracts, light rays traveling to the pupil. The shape of the cornea determines how much of the light is bent and whether the image will be focused correctly on the retina at the back of the eye. Once the light has passed through both refraction layers, it converges into a single focal point onto a small area. This is where photoreceptors start transforming...
3.2K
Anatomy of the Eyeball01:20

Anatomy of the Eyeball

7.5K
The eye is a spherical, hollow structure composed of three tissue layers. The outer layer — the fibrous tunic, comprises the sclera — a white structure — and the cornea, which is transparent. The sclera encompasses some of the ocular surface, most of which is not visible. However, the 'white of the eye' is distinctively visible in humans compared to other species. The cornea, a clear covering at the front of the eye, enables light penetration. The eye's middle...
7.5K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Surgical Management of Primary Congenital Glaucoma: Results of a Nationwide Descriptive Study in France (CONGLAU).

Clinical ophthalmology (Auckland, N.Z.)·2025
Same author

Simple reaction time to visual and auditory stimulation in glaucoma.

European journal of ophthalmology·2025
Same author

Visual Functions in Patients With Leber Hereditary Optic Neuropathy.

Journal of neuro-ophthalmology : the official journal of the North American Neuro-Ophthalmology Society·2024
Same author

Age Difference on the Spatial Scale of Object Categorization.

Experimental aging research·2024
Same author

Method to Quickly Map Multifocal Pupillary Response Fields (mPRF) Using Frequency Tagging.

Vision (Basel, Switzerland)·2024
Same author

Glaucoma-associated abnormalities in cortical activity during a visuocognitive task.

Clinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology·2023

Related Experiment Video

Updated: Sep 2, 2025

Full-Circle Cauterization of Limbal Vascular Plexus for Surgically Induced Glaucoma in Rodents
10:10

Full-Circle Cauterization of Limbal Vascular Plexus for Surgically Induced Glaucoma in Rodents

Published on: February 15, 2022

1.5K

Reduced peripheral vision in glaucoma and boundary extension.

Quentin Lenoble1, Adrien Lossouarn2, Jean-François Rouland2

  • 1Lille Neuroscience & Cognition, Université Lille, Lille, France.

Clinical & Experimental Optometry
|August 10, 2022
PubMed
Summary

Glaucoma patients exhibit greater spatial memory distortions, specifically boundary extension, impacting their perception of scenes and object sizes due to a reduced field of view. This affects spatial navigation and visual cognition in glaucoma.

Keywords:
Boundary extensionglaucomascene perceptionsizespatial memory

More Related Videos

Assessing Early Stage Open-Angle Glaucoma in Patients by Isolated-Check Visual Evoked Potential
07:11

Assessing Early Stage Open-Angle Glaucoma in Patients by Isolated-Check Visual Evoked Potential

Published on: May 25, 2020

6.5K
Glaucoma-inducing Procedure in an In Vivo Rat Model and Whole-mount Retina Preparation
08:30

Glaucoma-inducing Procedure in an In Vivo Rat Model and Whole-mount Retina Preparation

Published on: March 12, 2016

13.2K

Related Experiment Videos

Last Updated: Sep 2, 2025

Full-Circle Cauterization of Limbal Vascular Plexus for Surgically Induced Glaucoma in Rodents
10:10

Full-Circle Cauterization of Limbal Vascular Plexus for Surgically Induced Glaucoma in Rodents

Published on: February 15, 2022

1.5K
Assessing Early Stage Open-Angle Glaucoma in Patients by Isolated-Check Visual Evoked Potential
07:11

Assessing Early Stage Open-Angle Glaucoma in Patients by Isolated-Check Visual Evoked Potential

Published on: May 25, 2020

6.5K
Glaucoma-inducing Procedure in an In Vivo Rat Model and Whole-mount Retina Preparation
08:30

Glaucoma-inducing Procedure in an In Vivo Rat Model and Whole-mount Retina Preparation

Published on: March 12, 2016

13.2K

Area of Science:

  • Ophthalmology
  • Neuroscience
  • Cognitive Psychology

Background:

  • Peripheral vision is crucial for spatial navigation.
  • Visual cognition's impact on peripheral vision is understudied in glaucoma.
  • Boundary extension is a memory distortion where individuals recall seeing more of a scene than was presented.

Purpose of the Study:

  • To investigate the effects of glaucoma on spatial memory and visual perception.
  • To assess if glaucoma impacts the phenomenon of boundary extension.
  • To understand how reduced visual field in glaucoma affects memory for scenes and object size perception.

Main Methods:

  • 15 glaucoma patients and 15 controls viewed 10 natural scene photographs for 0.5s or 10s.
  • Participants drew each scene from memory after viewing.
  • A control experiment assessed drawing of isolated objects without scene context.

Main Results:

  • Glaucoma patients showed a 12% larger boundary extension than controls on average, significant for 4 scenes.
  • Patients with glaucoma tended to add more space between objects and scene edges.
  • In a control task, glaucoma patients drew isolated objects smaller than controls.

Conclusions:

  • Glaucoma's reduced field of view significantly impacts spatial memory for scenes.
  • Glaucoma affects the perception of object size.
  • Visual cognition deficits in glaucoma extend to spatial memory and size perception.