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Long-term 14-year survival with primary hepatic angiosarcoma.

Jason Chen1, Nelson Chen2

  • 1Hepatopancreatobiliary Surgery, Princess Alexandra Hospital, Woolloongabba, Queensland, Australia jasonchen_dd@hotmail.com.

BMJ Case Reports
|August 10, 2022
PubMed
Summary

Primary hepatic angiosarcoma (PHA) is a rare liver cancer. Early diagnosis, surgery, and surveillance offer prolonged survival, as demonstrated by the longest-surviving patient case report.

Keywords:
General surgeryHepatic cancerSurgery

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Area of Science:

  • Hepatobiliary surgery
  • Surgical oncology
  • Medical imaging

Background:

  • Primary hepatic angiosarcoma (PHA) is a rare and aggressive liver malignancy with a poor prognosis.
  • Diagnosis and management of PHA are challenging due to its rarity and aggressive nature.

Observation:

  • This case report details the longest-surviving patient with PHA documented in medical literature.
  • The patient underwent a right hemihepatectomy 14 years prior to this report.
  • Recurrence was detected via surveillance imaging 10 years post-initial surgery, necessitating a segment III segmentectomy.

Findings:

  • The patient received adjuvant radiotherapy for involved surgical margins after the segmentectomy.
  • No further recurrence has been observed on imaging to date.
  • The patient remains disease-free and is thriving in the community.

Implications:

  • Aggressive surgical resection, including repeat surgery for recurrence, is crucial for long-term survival in PHA.
  • Adjuvant radiotherapy may improve outcomes, particularly with involved surgical margins.
  • Ongoing surveillance imaging is vital for early detection of recurrence in PHA patients.