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Updated: Sep 2, 2025

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Development of a post-mortem human specimen flow model for advanced bleeding control training.

Suzanne M Vrancken1, Boudewijn L S Borger van der Burg2, Pieter W Stark3

  • 1Department of Surgery, Alrijne Hospital, Leiderdorp, the Netherlands; Trauma Research Unit, Department of Surgery, Erasmus MC, University Medical Center Rotterdam, Rotterdam, the Netherlands.

Injury
|August 10, 2022
PubMed

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Summary
This summary is machine-generated.

A new perfused post-mortem human specimen (PMHS) model with circulating flow allows realistic training for catastrophic bleeding control techniques. This model effectively mimics hemorrhage and improves skill acquisition.

Area of Science:

  • Medical Simulation
  • Trauma Surgery Training
  • Anatomical Modeling

Background:

  • Effective hemorrhage control is critical for survival in catastrophic bleeding cases.
  • Realistic training models are needed to practice life-saving bleeding control techniques.
  • Current training methods may lack the fidelity required for complex scenarios.

Purpose of the Study:

  • To develop a realistic perfused post-mortem human specimen (PMHS) flow model.
  • To create a model suitable for practicing various bleeding control techniques.
  • To evaluate the model's ability to mimic hemorrhage and facilitate skill acquisition.

Main Methods:

  • Utilized embalmed post-mortem human specimens (PMHS) in a laboratory setting.
  • Established circulating arteriovenous flow using hypertonic saline and cannulas.
Keywords:
Bleeding controlFlow modelHuman cadaverPerfusionTraining

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  • Developed and refined the model based on performance and identified challenges.
  • Main Results:

    • Achieved sustained circulating arteriovenous flow throughout the PMHS.
    • Successfully mimicked major hemorrhage and demonstrated effective bleeding control with a resuscitative endovascular balloon occlusion of the aorta (REBOA) catheter.
    • Observed that regional perfusion reduced tissue edema and enhanced model durability.

    Conclusions:

    • The perfused PMHS model with circulating flow is a feasible training tool for bleeding control.
    • Regional arteriovenous flow effectively reduces tissue edema and increases model durability.
    • Further research is needed to optimize edema reduction and enhance model longevity.