Functional Thermoresponsive Hydrogel Molecule to Material Design for Biomedical Applications
Sagar Pardeshi1, Fouad Damiri2, Mehrukh Zehravi3
1Department of Pharmaceutical Technology, University Institute of Chemical Technology, KBC North Maharashtra University, Jalgaon 425001, Maharashtra, India.
Polymers
|August 12, 2022
Summary
Thermosensitive hydrogels offer ideal properties for drug delivery and cell scaffolding due to their temperature-responsive structure and biocompatibility. This review covers their synthesis, applications, and commercial potential.
Area of Science:
- Materials Science
- Biomedical Engineering
- Polymer Chemistry
Background:
- Thermosensitive hydrogels exhibit rapid viscosity changes and 3D structure formation upon temperature shifts.
- Their minimal invasiveness, biocompatibility, and body clearance make them attractive for biomedical uses.
- These materials are explored as cell scaffolds and drug reservoirs.
Purpose of the Study:
- To provide a comprehensive review of thermosensitive hydrogels.
- To detail their synthesis, underlying mechanisms, and diverse biomedical applications.
- To explore the intellectual property landscape and commercial viability of these hydrogels.
Main Methods:
- Literature review of scientific publications.
- Analysis of patents and marketed products.
- Synthesis and characterization of thermosensitive hydrogels (implied).
Main Results:
- Thermosensitive hydrogels possess tunable properties for controlled release and tissue engineering.
- Successful applications demonstrated in drug delivery, regenerative medicine, and diagnostics.
- Significant commercial interest and existing market products highlight their potential.
Conclusions:
- Thermosensitive hydrogels are versatile biomaterials with broad biomedical applications.
- Further research and development are ongoing to optimize their performance and expand their use.
- The market for thermosensitive hydrogels is promising, with potential for innovation and commercial success.


