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Antibodies to normal and Alzheimer human brain structures from non-immunised mice of various ages

FEBS Letters
|June 8, 1987
PubMed

Supernatants from mouse spleen hybridoma lines established without previous immunisation were screened immunohistochemically against cryostat sections of human temporal cortex and found to stain a variety of brain structures, including Alzheimer plaques and tangles. The age of the mice had no effect on antibody production.

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