Related Experiment Video
Updated: Sep 1, 2025

Isolation, Processing and Analysis of Murine Gingival Cells
Published on: July 2, 2013
Plasma cell gingivitis: A perplexing and rare clinical entity
Muneesh Joshi1, T Prasanth1, Manab Kosala1
1Department of Periodontology, Armed Forces Medical College, Pune, Maharashtra, India.
Plasma cell gingivitis (PCG) presents a diagnostic challenge with fiery red, bleeding gums. This article details a rare case managed through comprehensive clinical, radiological, and histopathological analysis.
Area of Science:
- Oral Medicine
- Periodontology
- Dermatology
Background:
- Plasma cell gingivitis (PCG) is a rare inflammatory condition of the gingiva.
- It is characterized by a distinctive bright red appearance and spontaneous bleeding.
- PCG can be misdiagnosed as other gingival lesions, posing a clinical challenge.
Observation:
- The article discusses a specific rare case of plasma cell gingivitis.
- Clinical presentation included bright red, swollen gingiva with easy bleeding.
- Diagnostic workup involved detailed clinical examination, radiological imaging, histopathology, and immunohistochemistry.
Findings:
- Histopathological and immunohistochemical analyses confirmed the diagnosis of plasma cell gingivitis.
- The findings highlighted the characteristic infiltration of plasma cells in the gingival tissue.
- Exclusion of other potential causes was essential for accurate diagnosis.
Implications:
- Accurate diagnosis of PCG is vital for appropriate management and patient care.
- Understanding the distinct features of PCG aids clinicians in differentiating it from more common or serious oral conditions.
- This case underscores the importance of a multidisciplinary diagnostic approach for rare oral lesions.
Related Concept Videos
Transcytosis of IgG
IgG molecules from a mother undergo transcytosis starting around 13 weeks of gestation. The amount of IgG transferred and entering the fetal blood circulation increases with...
Endocarditis II: Clinical Features of Infective Endocarditis
Peptic Ulcer Disease III: Clinical Manifestations and Diagnostic Studies
Few clinical manifestations differentiate gastric ulcers from duodenal ulcers. Distinctions in the location, timing, and pain relief are crucial for healthcare providers in differentiating between gastric and duodenal ulcers during clinical assessments.
Gastritis III: Clinical Manifestations and Management
Clinical manifestations of acute gastritis
The patient with acute gastritis may have a rapid onset of symptoms, such as epigastric pain or discomfort, dyspepsia, anorexia, hiccups, or nausea and vomiting, which can last from a few hours to a few days. Erosive or hemorrhagic gastritis may cause bleeding, which may manifest as blood in vomit or as...
Pneumonia I: Introduction
Risk Factors
Various factors influence the likelihood of developing pneumonia. Age plays a crucial role, with infants, children under two, and individuals over 65 at increased risk due to their...
Chronic Kidney Disease II: Clinical Manifestations

