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Indel Detection following CRISPR/Cas9 Mutagenesis using High-resolution Melt Analysis in the Mosquito Aedes aegypti
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Genetic Toolbox Approaches in Mosquitoes
Olena Riabinina1, Matthew Quinn2, Joe P Whitehead2
1Department of Biosciences, Durham University, Durham, DH1 3LE, United Kingdom olena.riabinina@durham.ac.uk.
Cold Spring Harbor Protocols
|August 12, 2022
Abstract:
Mosquitoes are fascinating and diverse study organisms that are rapidly becoming genetically tractable. Here, we review the latest and most commonly used approaches to silence or edit genes and express transgenes in mosquitoes. We also focus on gene drives-a genetic technology that may prove essential for combating mosquito-borne diseases.

