Acquired pseudoobstruction of the colon due to segmental hypoganglionosis

A case of acquired pseudoobstruction of the colon due to segmental hypoganglionosis is reported. The patient became constipated during pregnancy and obstructive symptoms followed. Radiologically, the diseased segment was spastic and the proximal colon was extremely dilated. Microscopically, the involved segment showed marked diminution in the number of intramural ganglion cells and those present showed degenerative changes.