Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Incorporation of Organic Counter-Cations Into Poly(Heptazine Imide) Networks for Promoting Proton-Coupled Electron Transfer During Photocatalytic H<sub>2</sub>O<sub>2</sub> Evolution.

Angewandte Chemie (International ed. in English)·2026
Same author

Emerging Non-Conventional Approaches in mRNA-LNP Formulation for Therapeutic Applications.

Pharmaceutics·2026
Same author

Programmable Solid-Electrolyte Interfaces for Efficient and Selective Electrochemical Hydrogenations.

Angewandte Chemie (International ed. in English)·2026
Same author

Correction: Microbiome-inspired solutions to save human and planetary health.

Frontiers in microbiology·2026
Same author

Engineering synthetic cells with intramembrane domains possessing distinct bilayer asymmetries.

Nature communications·2026
Same author

Microbiome-inspired solutions to save human and planetary health.

Frontiers in microbiology·2026

Related Experiment Video

Updated: Sep 1, 2025

Particle Templated Emulsification enables Microfluidic-Free Droplet Assays
11:03

Particle Templated Emulsification enables Microfluidic-Free Droplet Assays

Published on: March 9, 2021

6.0K

Dewetting-Assisted Interface Templating: Complex Emulsions to Multicavity Particles.

Naresh Yandrapalli1, Markus Antonietti1

  • 1Max Planck Institute of Colloids and Interfaces, Department of Colloid Chemistry, Am Mühlenberg 1, 14476, Potsdam, Germany.

Advanced Science (Weinheim, Baden-Wurttemberg, Germany)
|August 12, 2022
PubMed
Summary

This study introduces a novel method using polydimethylsiloxane (PDMS) swelling to create complex emulsions. These transform into structured microparticles with intact membranes, useful for cargo delivery and biosensing.

Keywords:
complex emulsionsdewettingmicrofluidicsmulticavity particlesnanoindentationpolymersomesproptose emulsions

More Related Videos

Double Emulsion Generation Using a Polydimethylsiloxane PDMS Co-axial Flow Focus Device
08:58

Double Emulsion Generation Using a Polydimethylsiloxane PDMS Co-axial Flow Focus Device

Published on: December 25, 2015

16.2K
Facile Preparation of Internally Self-assembled Lipid Particles Stabilized by Carbon Nanotubes
09:47

Facile Preparation of Internally Self-assembled Lipid Particles Stabilized by Carbon Nanotubes

Published on: February 19, 2016

9.8K

Related Experiment Videos

Last Updated: Sep 1, 2025

Particle Templated Emulsification enables Microfluidic-Free Droplet Assays
11:03

Particle Templated Emulsification enables Microfluidic-Free Droplet Assays

Published on: March 9, 2021

6.0K
Double Emulsion Generation Using a Polydimethylsiloxane PDMS Co-axial Flow Focus Device
08:58

Double Emulsion Generation Using a Polydimethylsiloxane PDMS Co-axial Flow Focus Device

Published on: December 25, 2015

16.2K
Facile Preparation of Internally Self-assembled Lipid Particles Stabilized by Carbon Nanotubes
09:47

Facile Preparation of Internally Self-assembled Lipid Particles Stabilized by Carbon Nanotubes

Published on: February 19, 2016

9.8K

Area of Science:

  • Materials Science
  • Chemical Engineering
  • Nanotechnology

Background:

  • Microparticle fabrication relies on emulsion-templating for diverse geometries.
  • Traditional microfluidics face limitations in generating complex emulsion structures.

Purpose of the Study:

  • To develop a novel method for creating complex emulsions with multiple inner cores using PDMS swelling.
  • To investigate the transformation of these emulsions into structured microparticles with intact membranes.
  • To explore potential applications in cargo delivery, membrane transport, structural coloring, and biosensing.

Main Methods:

  • Utilizing polydimethylsiloxane (PDMS) swelling to generate water-in-styrene-in-water complex emulsions.
  • Employing block copolymer surfactant and gravity-driven dewetting for emulsion metamorphosis.
  • Polymerizing styrene to form solid microparticle structures with membranous compartments.

Main Results:

  • Reproducible formation of complex emulsions with multiple inner cores via PDMS swelling.
  • Transformation into membranous structures and subsequently solid microparticles with intricate geometries.
  • Demonstrated absence of polystyrene within membranes via mechanical and confocal microscopy.
  • Successful release of encapsulated gold nanoparticles through osmotic pressure-induced membrane rupture.
  • Observed light-scattering behavior in ruptured microparticles for advanced applications.

Conclusions:

  • PDMS-based swelling is a viable method for reproducible complex emulsion production.
  • The resulting microparticles can be tailored into membranous emulsions or solid structures.
  • These microparticles offer diverse applications in cargo delivery, biosensing, and structural coloring.