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Updated: Sep 1, 2025

Irradiator Commissioning and Dosimetry for Assessment of LQ α and β Parameters, Radiation Dosing Schema, and in vivo Dose Deposition
Published on: March 11, 2021
Technical note: Absolute dose measurements of a vault-free radiosurgery system
Stephen P Sorensen1, Shyam S Jani1, Dilini S Pinnaduwage1
1Department of Radiation Oncology, St. Joseph's Hospital and Medical Center, Phoenix, Arizona, USA.
Accurate absolute dose (AD) calibration for the ZAP-X radiosurgery system is crucial. Modified TG-21 protocols using a custom phantom offer a reliable alternative to TG-51, ensuring precise radiotherapy delivery.
Area of Science:
- Medical Physics
- Radiotherapy
- Dosimetry
Background:
- Accurate absolute dose (AD) calibration is vital for radiotherapy machine function.
- Many systems require modifications to meet TG-51 standards.
- TG-21 calibration offers a viable alternative with appropriate setup and factors.
Purpose of the Study:
- To evaluate modified TG-21 and TG-51 protocols for AD calibrations.
- To assess these protocols on the ZAP-X radiosurgery system.
- To utilize ion chambers, film, and thermoluminescent dosimeters (TLDs) for evaluation.
Main Methods:
- Utilized a custom acrylic phantom based on TG-21 and TRS-398 recommendations.
- Calculated AD using Nx and TG-21 parameters with a PTW 31010 chamber.
- Performed measurements in a PTW MP3-XS water tank using TG-51 factors.
- Verified dose with Gafchromic film and TLDs.
Main Results:
- Measurements from TG-51, modified TG-21, film, and TLDs showed agreement within ±2%.
- This indicates high consistency across different calibration methods.
Conclusions:
- Modified TG-51 in water is preferred but can be impractical due to setup challenges.
- The modified TG-21 protocol with a custom acrylic phantom is an accurate and practical alternative for ZAP-X dose calibration.
- Both methods provide confidence in the system's absolute dose calibration.
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