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Characterization of the novel HLA-C*03:613 allele by next generation sequencing

Valentine Jacob1,2, Judith Desoutter1, Nicolas Guillaume1,2

  • 1Department of Hematology and Histocompatibility, Amiens University Medical Center, Amiens, France.

HLA
|August 15, 2022
PubMed

Abstract:

HLA-C*03:613 differs from HLA-C*03:02:02 by one nucleotide substitution in codon 190 in exon 4.

Keywords:
HLA-C*03:613HLAnew allelenext-generation sequencing

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Next-generation Sequencing03:00

Next-generation Sequencing

The first human genome sequencing project cost $2.7 billion and was declared complete in 2003, after 15 years of international cooperation and collaboration between several research teams and funding agencies. Today, with the advent of next-generation sequencing technologies, the cost and time of sequencing a human genome have dropped over 100 fold.
Next-Generation Sequencing Methods
Although all next-generation methods use different technologies, they all share a set of standard features.

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