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RNA binding protein BOULE forms aggregates in mammalian testis

Yujuan Su1, Xinghui Guo1, Min Zang1

  • 1State Key Laboratory of Reproductive Medicine, Nanjing Medical University, Nanjing, Jiangsu 211166, China.

Journal of Biomedical Research
|August 15, 2022
PubMed
Summary

Non-pathological amyloids, like BOULE, form during mammalian sperm development. These amyloid-like protein aggregates bind to RNA, suggesting a role in reproduction.

Keywords:
BOULERNA-binding proteinSDD-AGEamyloidenhanced UV cross-linking immunoprecipitationprotein aggregation

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