Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Venous Thrombosis IV: Nursing Management

Venous Thrombosis IV: Nursing Management

Nursing management begins with a thorough assessment of the patient's health history. Key factors include trauma to veins, peripherally inserted central catheters, varicose veins, recent pregnancy or childbirth, surgery, bacteremia, prolonged bed rest, atrial fibrillation, COPD, heart failure, cancer, coagulation disorders, myocardial infarction, spinal cord injury, stroke, prolonged travel, recent bone fractures, and dehydration. Review medication intake, particularly oral contraceptives,...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Flexible, multimodal, electrical-sensing-optical-transmission μfiber-sensors via an on-fiber printed electronics strategy.

National science review·2026

Same author

Research progress and applications of functional hydrogels in nasal wound healing.

Journal of biological engineering·2026

Same author

Cigarette Smoke-Induced ClC-3 Deficiency Drives Chronic Bronchitis via the AKT/CREB1 Axis and Lysosomal-Autophagic Impairment.

Free radical biology & medicine·2026

Same author

Operational mechanisms and application advances in artificial olfactory systems.

Biomedical engineering online·2026

Same author

Analysis of Voiding Impairment Following Transperineal Prostate Biopsy: Do Alpha-Blockers Reduce the Risk?

ANZ journal of surgery·2026

Same author

Application of Digital Medicine to the Diagnosis and Treatment of Head and Neck Tumors.

Cancer reports (Hoboken, N.J.)·2026

Search research articles

Related Experiment Video

Updated: Sep 1, 2025

Leveraging Turbidity and Thromboelastography for Complementary Clot Characterization

Leveraging Turbidity and Thromboelastography for Complementary Clot Characterization

Published on: June 4, 2020

To Investigate Whether Hematocrit Affects Thromboelastography Parameters.

Min Zhang¹, Keyu He¹, Dong Ye²

¹Department of Blood Transfusion, Zhongda Hospital, School of Medicine, Southeast University, Nanjing 210009, China.

Contrast Media & Molecular Imaging

|August 15, 2022

Summary

This summary is machine-generated.

Hematocrit significantly impacts thromboelastogram (TEG) results, often overestimating coagulation in anemia. Correction formulas are essential for accurate TEG analysis in patients with low red blood cell counts.

More Related Videos

Erythrocyte Sedimentation Rate: A Physics-Driven Characterization in a Medical Context

Erythrocyte Sedimentation Rate: A Physics-Driven Characterization in a Medical Context

Published on: March 24, 2023

Hemocompatibility Testing of Blood-Contacting Implants in a Flow Loop Model Mimicking Human Blood Flow

Hemocompatibility Testing of Blood-Contacting Implants in a Flow Loop Model Mimicking Human Blood Flow

Published on: March 5, 2020

Related Experiment Videos

Last Updated: Sep 1, 2025

Leveraging Turbidity and Thromboelastography for Complementary Clot Characterization

Leveraging Turbidity and Thromboelastography for Complementary Clot Characterization

Published on: June 4, 2020

Erythrocyte Sedimentation Rate: A Physics-Driven Characterization in a Medical Context

Erythrocyte Sedimentation Rate: A Physics-Driven Characterization in a Medical Context

Published on: March 24, 2023

Hemocompatibility Testing of Blood-Contacting Implants in a Flow Loop Model Mimicking Human Blood Flow

Hemocompatibility Testing of Blood-Contacting Implants in a Flow Loop Model Mimicking Human Blood Flow

Published on: March 5, 2020

Area of Science:

Hematology
Coagulation Science

Background:

Thromboelastogram (TEG) is a crucial diagnostic tool for assessing whole blood coagulation function.
Red blood cells (RBCs), the most abundant blood component, may influence TEG test outcomes.
The specific impact of hematocrit (HCT) on TEG parameters requires detailed investigation.

Purpose of the Study:

To investigate the correlation between hematocrit (HCT) and thromboelastogram (TEG) parameters.
To develop correction formulas for TEG results in anemic patients.

Main Methods:

Analyzed the correlation between HCT and TEG parameters using 17 reconstituted blood samples with varying HCT levels.
Performed correction tests on 17 anemic patient samples, adjusting HCT to standard levels (0.40 for females, 0.45 for males).
Derived correction formulas based on experimental data to adjust TEG values for anemia.

Main Results:

A significant negative correlation was observed between HCT and TEG parameters (CI, angle, K).
Increased HCT levels led to decreased Clot Initiation (CI) and angle, and increased K time in reconstituted samples.
Correction tests revealed significant differences between measured and corrected TEG values in anemic samples, necessitating formula application.

Conclusions:

Hematocrit (HCT) negatively impacts thromboelastogram (TEG) measurements, potentially leading to an overestimation of coagulation status in anemic individuals.
TEG results for anemic patients require correction using established formulas or experimental adjustments for accurate clinical interpretation.
The derived correction formulas provide a method to adjust TEG parameters, improving diagnostic accuracy in the presence of anemia.