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Updated: Sep 1, 2025

Preparation of SNS CobaltII Pincer Model Complexes of Liver Alcohol Dehydrogenase
Published on: March 19, 2020
Synthesis and characterization of cobalt SCS pincer complexes
Jan Pecak1, Matthias Käfer1, Sarah Fleissner1
1Institute of Applied Synthetic Chemistry, Vienna University of Technology, Getreidemarkt 9/163-AC, 1060 Vienna, Austria.
Abstract:
The synthesis and characterization of two Co(II) complexes stabilized by a tridentate SCS pincer ligand are described. Paramagnetic [Co(κ3-SCSCH2-Et)2] and [Co(κ3-SCSCH2-tBu)(κ2-SCSCH2-tBu)] were obtained via transmetalation protocol from CoBr2 and S(C-Br)SCH2-R (R = Et, tBu). Oxidation of the latter with [Cp2Fe]PF6 affords the diamagnetic 18 VE complex [Co(κ3-SCSCH2-tBu)2]PF6. X-ray structures and DFT calculations are presented.
Supplementary Information:
The online version contains supplementary material available at 10.1007/s00706-022-02949-1.
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