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Colloidal gas aphrons for biotechnology applications: a mini review
Priyabrata Pal1, Shadi W Hasan1, Mohammad Abu Haija2
1Department of Chemical Engineering, Khalifa University of Science and Technology, Abu Dhabi, United Arab Emirates.
Critical Reviews in Biotechnology
|August 15, 2022
Summary
Colloidal gas aphrons (CGAs), stable surfactant-coated bubbles, show promise for recovering biomolecules like proteins and microalgae. Their unique properties facilitate efficient bio-separation, highlighting their biotechnological potential.
Area of Science:
- Colloid and surface science
- Biotechnology
- Separation science
Background:
- Colloidal gas aphrons (CGAs) are stable, micrometer-sized bubbles with surfactant multilayers.
- CGAs possess properties like high stability and large interfacial area, suitable for biotechnological applications.
Purpose of the Study:
- To review the bio-application of CGAs for recovering natural components.
- To present experimental results, challenges, and future research directions for CGA-based recovery.
Main Methods:
- Literature review of experimental studies on CGA bio-applications.
- Analysis of factors influencing biomolecule recovery via CGAs.
Main Results:
- Biomolecule recovery using CGAs is primarily driven by electrostatic or hydrophobic interactions.
- Successful recovery of proteins, yeast, and microalgae demonstrated.
Conclusions:
- CGAs offer a viable technology for biomolecule and natural component recovery.
- Knowledge transfer is crucial for the commercialization of CGA-based bio-product recovery.
