Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Glaucoma: Overview01:25

Glaucoma: Overview

705
Glaucoma is an eye condition characterized by increased intraocular pressure that damages the retina and optic nerve, leading to irreversible blindness if left untreated. The human eye has various components, including the cornea, iris, pupil, lens, and optic nerve. Aqueous humor is secreted by the epithelium of the ciliary body in the posterior chamber and flows through the trabecular meshwork and canal of Schlemm, maintaining normal intraocular pressure. The trabecular meshwork and the canal...
705
Angle Closure Glaucoma: Treatment01:28

Angle Closure Glaucoma: Treatment

632
Angle-closure glaucoma, or closed-angle glaucoma, is an eye condition where the iris bulges out and blocks the iridocorneal angle, resulting in a buildup of aqueous humor and increased intraocular pressure. Immediate medical attention is necessary due to the sudden onset of symptoms. The treatment for angle-closure glaucoma includes short-term and long-term approaches. Short-term treatment involves using eye drops like pilocarpine to lower intraocular pressure by increasing aqueous humor...
632
Open Angle Glaucoma: Treatment01:27

Open Angle Glaucoma: Treatment

534
In open-angle glaucoma, the iridocorneal angle remains open, but the trabecular meshwork becomes stiff, slowing down the outflow of aqueous humor. This causes a buildup of aqueous humor in the anterior chamber, leading to a sudden increase in intraocular pressure. The treatment for open-angle glaucoma focuses on reducing the elevated intraocular pressure by either decreasing the secretion of aqueous humor or increasing its outflow.
Drugs such as carbonic anhydrase inhibitors, α2- and...
534
Focusing of Light in the Eye01:16

Focusing of Light in the Eye

3.2K
Light rays enter the eye through the cornea, a transparent dome-shaped tissue that is the eye's outermost layer. The cornea bends or refracts, light rays traveling to the pupil. The shape of the cornea determines how much of the light is bent and whether the image will be focused correctly on the retina at the back of the eye. Once the light has passed through both refraction layers, it converges into a single focal point onto a small area. This is where photoreceptors start transforming...
3.2K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Global Consensus on Keratoconus and Ectatic Diseases-Edition 2.

Cornea·2026
Same author

Corrigendum to "TFOS DEWS III: Digest" Am J Ophthalmol. 2025; 279:451-553.

American journal of ophthalmology·2026
Same author

Long-Term Outcomes of Boston Type I Keratoprosthesis After Minor Salivary Gland Transplantation and Labial Mucous Membrane Grafting as an Alternative Treatment for Stevens-Johnson Syndrome.

Cornea·2025
Same author

Corneal Sensitivity with the Non-contact Esthesiometer as Compared to the Cotton Wisp Test in Patients with Ocular Surface Diseases.

Ophthalmology and therapy·2025
Same author

TFOS DEWS III.

American journal of ophthalmology·2025
Same author

TFOS DEWS III: Digest.

American journal of ophthalmology·2025

Related Experiment Video

Updated: Sep 1, 2025

Author Spotlight: Establishing a Practical and Cost-Effective Protocol for Corneal Sensitivity Testing in Clinical Settings
04:00

Author Spotlight: Establishing a Practical and Cost-Effective Protocol for Corneal Sensitivity Testing in Clinical Settings

Published on: August 2, 2024

2.2K

Keratoconus epidemiology: A review.

José A P Gomes1, Pablo F Rodrigues1, Luiz L Lamazales1

  • 1Department of Ophthalmology and Visual Sciences, Paulista Medical School/Federal University of São Paulo (EPM/UNIFESP), Sao Paulo, Brazil.

Saudi Journal of Ophthalmology : Official Journal of the Saudi Ophthalmological Society
|August 16, 2022
PubMed
Summary

Keratoconus, a corneal disease, affects young individuals and is influenced by eye rubbing, genetics, and environment. Its prevalence varies globally, reaching up to 5% in the Middle East.

Keywords:
Corneal ectasiaepidemiologykeratoconusprevalencerisk factors

More Related Videos

Three Different Protocols of Corneal Collagen Crosslinking in Keratoconus: Conventional, Accelerated and Iontophoresis
07:29

Three Different Protocols of Corneal Collagen Crosslinking in Keratoconus: Conventional, Accelerated and Iontophoresis

Published on: November 12, 2015

20.0K
Author Spotlight: Anterior HR-OCT as a Non-Invasive Tool for Characterizing Ocular Surface Squamous Neoplasia
06:15

Author Spotlight: Anterior HR-OCT as a Non-Invasive Tool for Characterizing Ocular Surface Squamous Neoplasia

Published on: August 9, 2024

1.4K

Related Experiment Videos

Last Updated: Sep 1, 2025

Author Spotlight: Establishing a Practical and Cost-Effective Protocol for Corneal Sensitivity Testing in Clinical Settings
04:00

Author Spotlight: Establishing a Practical and Cost-Effective Protocol for Corneal Sensitivity Testing in Clinical Settings

Published on: August 2, 2024

2.2K
Three Different Protocols of Corneal Collagen Crosslinking in Keratoconus: Conventional, Accelerated and Iontophoresis
07:29

Three Different Protocols of Corneal Collagen Crosslinking in Keratoconus: Conventional, Accelerated and Iontophoresis

Published on: November 12, 2015

20.0K
Author Spotlight: Anterior HR-OCT as a Non-Invasive Tool for Characterizing Ocular Surface Squamous Neoplasia
06:15

Author Spotlight: Anterior HR-OCT as a Non-Invasive Tool for Characterizing Ocular Surface Squamous Neoplasia

Published on: August 9, 2024

1.4K

Area of Science:

  • Ophthalmology
  • Genetics
  • Epidemiology

Background:

  • Keratoconus is a progressive, ectatic corneal disease affecting young individuals.
  • Risk factors include eye rubbing, environmental exposures, and genetic predispositions.
  • Prevalence varies significantly, with rates as high as 5% reported in the Middle East.

Purpose of the Study:

  • To review and synthesize current epidemiological data on keratoconus.
  • To discuss the characteristics and risk factors associated with keratoconus.
  • To correlate epidemiological findings with the pathogenesis of keratoconus.

Main Methods:

  • Systematic literature search of English-language studies on PubMed.
  • Inclusion of relevant epidemiological studies on keratoconus.
  • Analysis and discussion of study findings on prevalence, characteristics, and risk factors.

Main Results:

  • Keratoconus affects both genders, typically presenting in adolescence or early adulthood.
  • Key risk factors identified are eye rubbing, environmental influences, and genetic factors.
  • Epidemiological data indicate a variable prevalence, notably high in certain regions like the Middle East.

Conclusions:

  • Understanding keratoconus epidemiology is crucial for public health and clinical management.
  • Further research is needed to elucidate the complex interplay of genetic and environmental factors in keratoconus pathogenesis.
  • Targeted interventions for high-risk populations may help mitigate keratoconus progression.