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Updated: Sep 1, 2025

Eye Tracking Young Children with Autism
Published on: March 27, 2012
Intensive behavioural interventions based on applied behaviour analysis (ABA) for young children with autism: A
Robert Hodgson1, Mousumi Biswas2, Stephen Palmer3
1Centre for Reviews and Dissemination, University of York, York, United Kingdom.
Insights
Early intensive Applied Behaviour Analysis (ABA) interventions for autistic children in the UK show higher costs and uncertain value for money. Further research is needed to clarify long-term outcomes and cost-effectiveness.
Area of Science:
- Health Economics
- Developmental Pediatrics
- Behavioral Science
Background:
- Autism Spectrum Disorder (ASD) presents significant economic and social burdens.
- Early intervention is crucial for improving outcomes in autistic children.
- Applied Behaviour Analysis (ABA) is a common intervention approach for ASD.
Purpose of the Study:
- To evaluate the cost-effectiveness of early intensive ABA-based interventions for pre-school autistic children in the UK.
- To compare ABA interventions with treatment as usual (TAU) from a public sector perspective.
Main Methods:
- A de novo economic analysis using a 15.5-year time horizon.
- Individual patient data (IPD) meta-analysis informed the model.
- Costs and benefits were discounted at 3.5% annually.
Main Results:
- Early intensive ABA therapies incurred higher costs but yielded greater benefits.
- The incremental cost-effectiveness ratio (ICER) ranged from £46,768 to £189,122 per QALY, depending on assumptions.
- Adult outcomes and school type significantly influenced the analysis results.
Conclusions:
- Early intensive ABA interventions are unlikely to meet UK healthcare funding thresholds (£20,000-£30,000/QALY).
- Evidence gaps regarding long-term outcomes limit definitive conclusions.
- Further research on post-intervention trajectories is recommended.
Background:
The economic and social costs of autism are significant. This study evaluates the cost-effectiveness of early intensive Applied Behaviour Analysis (ABA)-based interventions for autistic pre-school children in the UK.
Methods:
A de novo economic analysis was developed in Microsoft Excel comparing early intensive ABA-based interventions compared with treatment as usual (TAU). The analysis used 15.5-year time horizon, with costs and benefits discounted a 3.5%. The model structure was based on cohort structure to capture changes in adaptive behaviour and cognitive ability over time. The analysis was informed by an individual patient data (IPD) meta-analysis of available evidence.
Results:
Adopting a public sector perspective, early intensive ABA-based therapies were associated with greater incremental costs and greater benefits. When pessimistic assumptions were made regarding the long-term effects of treatment incremental costs were £46,103 and incremental quality-adjusted life years (QALYs) were 0.24, resulting in an incremental cost-effectiveness ratio (ICER) of £189,122 per quality-adjusted life year (QALY). When optimistic assumptions were made about long-term effects, incremental costs were £39,233 with incremental benefits of 0.84 QALYs. The resulting ICER was £46,768 per QALY. Scenario analyses emphasised the importance of assumptions made regarding adult outcomes and type of school attended, both of which significantly affect the results of the analysis.
Conclusions:
The results of this economic analysis suggest that early intensive ABA-based interventions are unlikely to represent value for money, based on a £20,000 to £30,000 per QALY threshold typically adopted to inform UK healthcare funding decisions. However, important gaps in the available evidence, limit the strength of the conclusions that can be drawn from the presented analysis. Further research, focusing on the trajectory of autistic children following intervention is likely to be highly beneficial to resolving some of these uncertainties.
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