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Updated: Sep 1, 2025

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Author Spotlight: Biological Standardization to Ensure Reproducibility and Harmonization in Research
Published on: August 4, 2023
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CUF-Links: Continuous and Ubiquitous FAIRness Linkages for reproducible research
1Argonne National Laboratory & The University of Chicago.
Summary
Reproducible research is difficult due to lost connections. Simple methods capturing data flow create Continuous and Ubiquitous FAIRness linkages (CUF-links), enabling reproducible computational steps.
Area of Science:
- Computational science
- Data science
- Research methodology
Background:
- Reproducibility in computational research is a persistent challenge.
- Existing tools often fail to capture complex interdependencies in research projects.
- Difficulty in tracking data lineage hinders the verification of research results.
Purpose of the Study:
- To present simple methods for preserving interstitial connections in research processes.
- To enhance the capture of provenance linkages essential for reproducible research.
- To extend the scope of findable, accessible, interoperable, and reusable (FAIR) data.
Main Methods:
- Integrating simple data capture mechanisms into existing work practices.
- Recording information on all data products consumed or produced within a project.
- Establishing Continuous and Ubiquitous FAIRness linkages (CUF-links) from inputs to outputs.
Main Results:
- Demonstrated methods for capturing basic information about data flow.
- Facilitated the creation of a continuous chain of provenance linkages.
- Showcased practical applications of the proposed methods.
Conclusions:
- Simple, integrated methods can significantly improve research reproducibility.
- CUF-links enhance data provenance and support FAIR data principles.
- The proposed approach aids in overcoming challenges in complex computational research.
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