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Updated: Sep 1, 2025

In Vivo Functional Study of Disease-associated Rare Human Variants Using Drosophila
Published on: August 20, 2019
Using FlyBase: A Database of Drosophila Genes and Genetics
Victoria K Jenkins1, Aoife Larkin2, Jim Thurmond3
1The Biological Laboratories, Harvard University, Cambridge, MA, USA. vjenkins@morgan.harvard.edu.
Abstract:
Since 1992, FlyBase has provided a freely available online database of information about the model organism Drosophila melanogaster. Data in FlyBase is curated manually from research papers as well as computationally from a variety of relevant sources, to serve as an information hub that enables and accelerates research discovery. This chapter aims to give users new to the database an overview of the layout and types of data available, as well as introducing some tools with which to access the data. More experienced users will find useful information about recent improvements and descriptions to enable more efficient navigation of the database.

