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Extensive Pleural Involvement in Pediatric T-Cell Lymphoblastic Lymphoma
Bela Jain1, Vivek Kumar Saini1, Ayush Mishra1
1Department of Nuclear Medicine, Sanjay Gandhi Postgraduate Institute of Medical Sciences, Lucknow, Uttar Pradesh, India.
Summary
T-cell lymphoblastic lymphoma (T-LBL) is a common childhood cancer. This case highlights rare, extensive pleural involvement in a pediatric T-LBL patient, emphasizing the need for reporting such unusual presentations.
Area of Science:
- Pediatric Oncology
- Hematology
- Medical Imaging
Background:
- Lymphoblastic lymphoma (LBL) is a prevalent non-Hodgkin lymphoma in pediatric populations.
- T-cell LBL (T-LBL) commonly presents with anterior mediastinal masses and disseminated disease.
Observation:
- A 12-year-old female presented with a year of progressive neck swelling and dyspnea.
- Diagnostic imaging revealed widespread hypermetabolic lymphadenopathy, splenic, bone marrow, and extensive left pleural involvement.
- Histopathological analysis confirmed T-cell LBL.
Findings:
- The patient was diagnosed with T-cell lymphoblastic lymphoma.
- Extensive secondary pleural involvement was a significant finding in this pediatric case.
- Diagnostic imaging, including FDG-PET/CT, was crucial for staging and revealing the extent of disease.
Implications:
- This case underscores the rare but possible extensive pleural manifestation of pediatric T-LBL.
- Reporting such unusual presentations is vital for refining understanding and diagnostic approaches to pediatric T-LBL.
- Further research may explore the specific mechanisms and clinical significance of pleural involvement in T-LBL.
Keywords:
Fluorodeoxyglucose positron-emission tomography/computed tomographyPediatric non-Hodgkin lymphomaT-cell lymphoblastic lymphomapleural lymphomaMore Related Videos
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