Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Behavioral Genetics and Its Designs01:23

Behavioral Genetics and Its Designs

486
Behavior genetics explores how genetic inheritance influences human behavior. It focuses on how genes, passed from parents to offspring, contribute to the development of behavioral traits and tendencies. This branch of genetics seeks to understand the complex interplay between inherited genetic factors and environmental influences in shaping our behaviors.
The primary methodologies used in behavior genetics include family studies, twin studies, and adoption studies, each providing unique...
486
Human Genetics01:28

Human Genetics

696
Human genetics provides a profound framework for understanding the interplay between genetic predispositions and human psychology. At the heart of this discipline lies the study of how genes influence physical traits, behaviors, and susceptibility to diseases. Each person carries a unique genetic code that subtly or significantly shapes their psychological and behavioral landscape.
The complex relationship between genetics and psychology is observable through common biological components such...
696
Conduct Disorder01:28

Conduct Disorder

103
Conduct disorder is a complex mental health diagnosis characterized by a repetitive and persistent pattern of behavior that violates societal norms, the rights of others, or age-appropriate rules. The diagnostic criteria for conduct disorder require the presence of at least three problematic behaviors within the past 12 months, with at least one occurring in the past six months. These behaviors are grouped into four categories: aggression toward people and animals; destruction of property;...
103
Attention-Deficit/Hyperactivity Disorder01:30

Attention-Deficit/Hyperactivity Disorder

171
Attention-deficit/hyperactivity disorder (ADHD) is a neurodevelopmental disorder characterized by persistent inattention, hyperactivity, and impulsivity. It affects approximately 5-8% of children globally, with around 60-70% of cases persisting into adulthood. ADHD has significant implications for educational attainment, social interactions, and occupational success.
Diagnostic Criteria and Symptoms
To diagnose ADHD, symptoms must manifest before age 12 and be evident across multiple settings....
171
Longitudinal Studies01:26

Longitudinal Studies

216
Longitudinal studies are also widely used in other medical and social science fields. For instance, in cardiovascular research, they can monitor patients' health over decades to identify risk factors for heart disease, such as high cholesterol or smoking, and evaluate the long-term effectiveness of preventive measures. Similarly, in mental health studies, researchers might follow individuals from adolescence into adulthood to understand the development and progression of conditions like...
216
Gene-Environment Interactions01:20

Gene-Environment Interactions

421
Gene expression is a dynamic process that is significantly influenced by environmental factors. This interaction underlies the complex nature of biological development and the phenotypic differences observed among individuals, even among those with identical genetic makeups. Factors such as radiation, temperature, behavior, nutrition, and stress play pivotal roles in determining how genes are expressed. The concept of the reaction range is central to understanding this interaction. It posits...
421

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Disentangling shared and unique effects of parenting on psychopathology: Evidence from two prospective, genetically sensitive cohort studies.

JCPP advances·2026
Same author

Triangulating evidence for genetic and environmental components of associations between parental behaviours and aggressive behaviour in children.

Nature communications·2026
Same author

Longitudinal Evidence for Age- and Sex-Invariant Dimensions of Internalizing Symptoms from Childhood through Adolescence: Self-Worth, Social Anxiety, and Withdrawal.

Research on child and adolescent psychopathology·2026
Same author

Maternal Distress Due to the COVID-19 Pandemic and Changes in Young Children's Behavior.

Journal of developmental and behavioral pediatrics : JDBP·2026
Same author

The Role of Harsh Discipline in Early Childhood Trajectories of Anxiety and Depressive Symptoms.

Academic pediatrics·2026
Same author

Parental Cognitive Stimulation of Young Children Before and After the Onset of the COVID-19 Pandemic.

Journal of developmental and behavioral pediatrics : JDBP·2026

Related Experiment Video

Updated: Aug 31, 2025

Moderate Prenatal Alcohol Exposure and Quantification of Social Behavior in Adult Rats
11:01

Moderate Prenatal Alcohol Exposure and Quantification of Social Behavior in Adult Rats

Published on: December 14, 2014

9.8K

Developmental genetic effects on externalizing behavior and alcohol use: Examination across two longitudinal samples.

Kit K Elam1, Kaitlin E Bountress2, Thao Ha3

  • 1Department of Applied Health Science, Indiana University, Bloomington, IN, USA.

Development and Psychopathology
|August 19, 2022
PubMed
Summary

Genetic predisposition for alcohol use disorder may increase the risk of externalizing behaviors and alcohol consumption during development. This genetic risk appears more pronounced in European Americans than African Americans.

Keywords:
adolescencealcohol useexternalizinglongitudinalpolygenic

More Related Videos

Chronic Intermittent Ethanol Vapor Exposure Paired with Two-Bottle Choice to Model Alcohol Use Disorder
05:12

Chronic Intermittent Ethanol Vapor Exposure Paired with Two-Bottle Choice to Model Alcohol Use Disorder

Published on: June 23, 2023

1.0K
Wheel Running and Environmental Complexity as a Therapeutic Intervention in an Animal Model of FASD
06:09

Wheel Running and Environmental Complexity as a Therapeutic Intervention in an Animal Model of FASD

Published on: February 2, 2017

6.9K

Related Experiment Videos

Last Updated: Aug 31, 2025

Moderate Prenatal Alcohol Exposure and Quantification of Social Behavior in Adult Rats
11:01

Moderate Prenatal Alcohol Exposure and Quantification of Social Behavior in Adult Rats

Published on: December 14, 2014

9.8K
Chronic Intermittent Ethanol Vapor Exposure Paired with Two-Bottle Choice to Model Alcohol Use Disorder
05:12

Chronic Intermittent Ethanol Vapor Exposure Paired with Two-Bottle Choice to Model Alcohol Use Disorder

Published on: June 23, 2023

1.0K
Wheel Running and Environmental Complexity as a Therapeutic Intervention in an Animal Model of FASD
06:09

Wheel Running and Environmental Complexity as a Therapeutic Intervention in an Animal Model of FASD

Published on: February 2, 2017

6.9K

Area of Science:

  • Behavioral Genetics
  • Developmental Psychology
  • Psychopathology

Background:

  • Externalizing behaviors in early adolescence are linked to later alcohol use, suggesting a developmental sequence.
  • Heterotypic continuity, where different behaviors share an underlying etiology, may explain this pattern.
  • A shared genetic basis is hypothesized for externalizing and substance use disorders.

Purpose of the Study:

  • To investigate if polygenic risk for alcohol use disorder predicts externalizing behavior and alcohol use.
  • To examine these predictions across developmental stages (early adolescence to early adulthood) and in different ancestral groups.

Main Methods:

  • Utilized two independent samples: Early Steps Multisite and Project Alliance 1 (PAL1).
  • Assessed polygenic risk scores for alcohol use disorder.
  • Examined associations with externalizing behavior and alcohol use in European American and African American participants separately.

Main Results:

  • In European Americans from the Early Steps sample, higher polygenic risk predicted externalizing behavior in early adolescence.
  • In European Americans from the PAL1 sample, higher polygenic risk predicted alcohol use in early adulthood.
  • These associations were largely absent in African American participants in both samples.

Conclusions:

  • Genetic predisposition for alcohol use disorder may contribute to the developmental emergence of externalizing and alcohol use behaviors.
  • Findings suggest differential genetic influences on these behaviors across ancestral groups.
  • Highlights the role of genetic risk in the developmental continuity of externalizing and substance use pathways.