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Phytocosmetic Containing Pink Pepper Extracts Obtained by Sustainable Extraction
Bruno Guzzo Silva1, Letícia Caramori Cefali2, Paulo de Tarso Vieira E Rosa3
1Center of Natural and Human Sciences (CCNH), Federal University of ABC (UFABC), Avenue of the States, 5001, Zip Code, 09210-580, Santo André, São Paulo, Brazil.
Chemistry & Biodiversity
|August 19, 2022
Summary
Pink pepper extract, optimized using supercritical carbon dioxide, shows significant antioxidant potential. A topical formulation retained this activity, demonstrating its viability for commercial applications.
Area of Science:
- Phytochemistry
- Cosmetic Science
- Natural Product Extraction
Background:
- Pink pepper (Schinus terebinthifolius Raddi) possesses valuable biological properties, including anti-inflammatory, antitumor, and antioxidant activities.
- These properties suggest significant commercial potential for pink pepper in various industries.
- Supercritical carbon dioxide extraction is an efficient method for obtaining bioactive compounds from plant materials.
Purpose of the Study:
- To investigate the antioxidant activity of pink pepper extract obtained via supercritical carbon dioxide extraction.
- To determine the optimal extraction parameters (pressure and temperature) for maximizing antioxidant potential.
- To evaluate the antioxidant efficacy and stability of a topical formulation containing the optimized pink pepper extract.
Main Methods:
- Supercritical carbon dioxide extraction was employed to obtain pink pepper extracts, varying pressure (100-300 bar) and temperature (40-60°C).
- Antioxidant activity was assessed using the α,α-diphenyl-β-picrylhydrazyl (DPPH) assay.
- The optimized extract was incorporated into an oil-in-water emulsion (2% m/m), and its properties and stability were evaluated.
Main Results:
- Extracts produced at 50-60°C exhibited high DPPH radical scavenging activity (80.16-91.27%), irrespective of extraction pressure.
- Optimized extraction conditions (200 bar, 50°C) yielded an extract with significant antioxidant capacity.
- The resulting topical formulation displayed desirable physical characteristics (creamy texture, color, odor, pH) and maintained 35.38% DPPH inhibition after storage.
Conclusions:
- Supercritical carbon dioxide extraction effectively isolates pink pepper compounds with potent antioxidant activity.
- Temperature is a critical factor in maximizing the antioxidant efficacy of pink pepper extracts.
- The developed topical formulation is stable and retains significant antioxidant properties, highlighting its commercial viability.
