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Plaquing of Herpes Simplex Viruses
Published on: November 5, 2021
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Genital Herpes Simplex Virus-An Updated Review
Saida Omarova1, Aileen Cannon1, Wendy Weiss1
1Department of Pediatrics, USF Morsani College of Medicine, 4202 East Fowler Avenue, SHS 100, Tampa, FL 33620, USA.
Advances in Pediatrics
|August 19, 2022
Summary
Herpes simplex viruses (HSV-1 and HSV-2) cause lifelong infections. Although their prevalence has decreased, these herpes viruses still cause significant health issues.
Area of Science:
- Virology
- Dermatology
- Infectious Diseases
Background:
- The herpes virus family (Herpesviridae) has over 200 members, with 8 known to infect humans.
- Human herpes viruses are classified into three subfamilies: Alphaherpesvirinae, Betaherpesvirinae, and Gammaherpesvirinae.
- Alphaherpesvirinae includes simplex viruses (HSV-1, HSV-2) and varicellovirus (varicella zoster virus).
Purpose of the Study:
- To provide an overview of the herpes virus family, focusing on human pathogens.
- To highlight the clinical significance of herpes simplex virus infections.
Main Methods:
- Review of existing literature on herpes virus classification and human infections.
- Analysis of prevalence trends and associated morbidities of HSV-1 and HSV-2.
Main Results:
- Herpes simplex viruses (HSV-1 and HSV-2) are significant human pathogens causing lifelong infections.
- Prevalence of HSV-1 and HSV-2 infections in the US has declined over the last two decades.
- Despite decreased prevalence, HSV infections continue to cause substantial clinical and psychological morbidity.
Conclusions:
- Herpes simplex viruses remain a public health concern due to their persistent nature and associated health burdens.
- Understanding herpes virus diversity and impact is crucial for managing infections.
