Toxoplasmosis diagnostic techniques: Current developed methods and biosensors.

Area of Science:

• Medical Parasitology
• Biotechnology
• Infectious Diseases

Background:

• Toxoplasma gondii is a ubiquitous parasite infecting numerous vertebrate hosts worldwide.
• Infection poses significant risks to fetuses and immunocompromised individuals.
• Accurate and rapid detection methods are crucial for patient management.

Purpose of the Study:

• To review recent molecular laboratory methods for Toxoplasma infection detection.
• To discuss rapid diagnostic methods, focusing on biosensors for point-of-care use.
• To emphasize the need for timely and precise toxoplasmosis diagnosis.

Main Methods:

• Review of molecular detection techniques for Toxoplasma gondii.
• Analysis of rapid diagnostic tools, including optical and electrochemical biosensors.
• Focus on point-of-care (POC) diagnostic capabilities.

Main Results:

• Molecular methods offer high sensitivity and specificity for Toxoplasma detection.
• Rapid biosensors show promise for quick, on-site diagnosis.
• Emerging technologies aim for improved accuracy and reduced detection times.

Conclusions:

• Advanced molecular and biosensor technologies are vital for effective toxoplasmosis management.
• Point-of-care biosensors represent a significant advancement for rapid diagnosis.
• Continued development is needed to enhance accessibility and performance of diagnostic tools.