Related Experiment Video
Updated: Aug 31, 2025
Competing-Risk Nomogram for Predicting Cancer-Specific Survival in Multiple Primary Colorectal Cancer Patients after Surgery
Published on: September 27, 2024
Development of a nomogram for predicting nosocomial infections among patients after cardiac valve replacement surgery
Xue Yao1,2, Na Li1,2, Ranran Lu1,2
1School of Nursing and Rehabilitation, Shandong University, Jinan, China.
Aims And Objectives:
To construct a predictive nomogram of the risk of nosocomial infections among patients after cardiac valve replacement surgery.
Background:
Nosocomial infections are a standout challenge that worsens the prognosis of patients after valve replacement surgery. However, studies on the nomogram of nosocomial infections in these patients have remained scarce.
Design:
A retrospective cohort study.
Methods:
Patients (n = 720) following valve replacement surgery from 2018 to 2019 were selected. LASSO regression and multivariate logistic regression were utilised to ascertain predictors of nosocomial infections. The predictive performance of the nomogram was appraised by calibration and discrimination. Decision and impact curves were used to assess the clinical utility. Internal validation was implemented via 1000 bootstrap samples to mitigate overfitting. TRIPOD guidelines were used in this study.
Results:
One hundred and fifty one patients (20.97%) experienced nosocomial infections following valve replacement surgery. Heart failure, preoperative anaemia, valve material, American Society of Anesthesiologists score ≥ IV, prolonged duration of surgery, duration of mechanical ventilation ≥ 24 h and indwelling nasogastric tube were predictors of nosocomial infections. Using these variables, we developed a predictive nomogram of the occurrence of nosocomial infections and the internal validation results demonstrated good discrimination and calibration of the nomogram. The clinical decision and impact curve revealed significant clinical utility.
Conclusions:
The present study constructed a nomogram for predicting the risk of nosocomial infections in patients following cardiac valve replacement surgery. This nomogram may strengthen the effective screening of patients at high risk of nosocomial infections.
Relevance To Clinical Practice:
This risk warning tool can assist clinical staff in making decisions and providing individualised infection control measures for patients, which has a significant reference value for clinical practice.
No Patient Or Public Contribution:
The data for this study were obtained from the hospital database, and the entire process of the study did not involve patient participation.
Related Concept Videos
01:27Mitral Stenosis IV: Nursing Management
01:29Endocarditis IV: Nursing Management
01:28Cardiomyopathy VII: Pre and Post Operative Nursing Management
01:18Endocarditis III: Medical Management
01:22Healthcare Associated Infections II: Preventive Measures
The best practices for preventing healthcare-associated infections include hand hygiene, patient risk...
01:26Factors Affecting the Risk of Infection
The integrity and count of the white blood cells help the body resist pathogens and fight infection. When impaired, it reduces the body's resistance to pathogens. The acidic pH levels of the gastrointestinal, genitourinary tracts, and skin...