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Updated: Aug 31, 2025
In vivo Optogenetic Stimulation of the Rodent Central Nervous System
Published on: January 15, 2015
Shedding light on current trends in molecular optogenetics
Alexandra A M Fischer1, Markus M Kramer1, Gerald Radziwill1
1Signalling Research Centres BIOSS and CIBSS, University of Freiburg, Schänzlestraße 18, 79104 Freiburg, Germany; Faculty of Biology, University of Freiburg, Schänzlestraße 18, 79104 Freiburg, Germany; Spemann Graduate School of Biology and Medicine (SGBM), University of Freiburg, Albertstrasse 21a, 79104 Freiburg, Germany.
Abstract:
Molecular optogenetics is a highly dynamic research field. In the past two years, the field was characterized by the development of new allosteric switches as well as the forward integration of optogenetics research towards application. Further, two areas of research have significantly gathered momentum, the use of optogenetics to control liquid-liquid phase separation as well as the application of optogenetic tools in the extracellular space. Here, we review these areas and discuss future directions.
